| Controlled trial of oxygen in uncomplicated myocardial infarction. | |
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MedLine Citation:
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PMID: 773507 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two-hundred consecutive patients thought to have suffered a myocardial infarction were admitted to a randomised, double-blind controlled trial of oxygen or air administered by MC mask throughout the first 24 hours in hospital. Forty-three patients in whom myocardial infarction was not subsequently confirmed were excluded from the analysis. The remaining air and oxygen groups were comparable except for a significantly higher PaO2 and serum aspartate aminotransferase level in the oxygen group. There was no significant difference in mortality, incidence of arrhythmias, use of analgesics, or systolic time intervals between the two groups, although a higher incidence of sinus tachycardia was found in those given oxygen. There appears to be no evidence of benefit from the routine administration of oxygen in uncomplicated myocardial infarction. |
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Authors:
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J M Rawles; A C Kenmure |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: British medical journal Volume: 1 ISSN: 0007-1447 ISO Abbreviation: Br Med J Publication Date: 1976 May |
Date Detail:
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Created Date: 1976-08-02 Completed Date: 1976-08-02 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0372673 Medline TA: Br Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1121-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Air Pressure Arrhythmias, Cardiac / complications Aspartate Aminotransferases / blood Clinical Trials as Topic Female Humans Male Middle Aged Myocardial Infarction / complications, enzymology, therapy* Oxygen / blood Oxygen Inhalation Therapy* Tachycardia / complications |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen; EC 2.6.1.1/Aspartate Aminotransferases |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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