| Controlled, prospective trial of psychosocial function before and after mandibular advancement splint therapy. | |
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MedLine Citation:
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PMID: 21536199 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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INTRODUCTION: The aim of the study was to investigate psychosocial function in patients with obstructive sleep apnea/hypopnea syndrome (OSAHS), before and after mandibular advancement splint (MAS) therapy. METHODS: In a prospective, parallel-group study, changes in psychosocial scores were compared before and after MAS therapy for OSAHS. Patients from the top (MAS treated, n = 40) or bottom (conservatively treated n = 35) of a MAS waiting list rated quality of life (Short Form 36 [SF-36] Health Survey) and sleepiness (Epworth Sleepiness Scale [ESS]). Both groups' ratings at baseline were completed while on conservative therapy. RESULTS: Baseline variables did not differ between groups. At follow-up, psychosocial scores showed improvement in MAS-treated patients, with odds ratios (confidence interval) of 0.26 (0.09, 0.75) and 0.36 (0.14, 0.92) for sleepiness and energy/vitality domain, respectively. Statistically significant improvement in the median (range) sleepiness score (10 [1 to 18] to 6 [1 to 14]; P <0.001) and energy/vitality domain (18 [7 to 20] to 19 [14 to 20]; P = 0.03) were observed with MAS therapy. Reductions were detected in median apnea-hypopnea index (median [range] 16 [5.2 to 30] to 4.6 [0.8 to 17.2] events/hour; P <0.001), and oxygen desaturation index (ODI) (11 [3 to 16] to 0 [0 to 5] events/hour; P <0.001) at follow-up with MAS therapy. Similar changes were observed in the comparison group when they went on to be treated with MAS. CONCLUSIONS: This study demonstrated that treatment with MAS produced statistically and clinically significant psychosocial and cardio-respiratory improvements. |
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Authors:
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Ama Johal; Joanna Battagel; Mark Hector |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics Volume: 139 ISSN: 1097-6752 ISO Abbreviation: Am J Orthod Dentofacial Orthop Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-05-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610224 Medline TA: Am J Orthod Dentofacial Orthop Country: United States |
Other Details:
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Languages: eng Pagination: 581-7 Citation Subset: D; IM |
Copyright Information:
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Copyright © 2011 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Senior lecturer, Barts and The London School of Medicine and Dentistry, Institute of Dentistry, London, United Kingdom. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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