Document Detail

Controlled ovarian hyperstimulation in women with polycystic ovarian syndrome with or without intrauterine insemination.
MedLine Citation:
PMID:  22122754     Owner:  NLM     Status:  Publisher    
Objective: To evaluate the value of intrauterine insemination (IUI) in controlled ovarian hyperstimulation (COH) among couples with polycystic ovary syndrome (PCOS) and normal semen analysis. Design: Retrospective cohort study Setting: University teaching center. Patients: PCOS couples with normal semen analysis that underwent COH with IUI or timed intercourse (TIC). Intervention: COH with clomiphene citrate, letrozole or gonadotropins with or without IUI. Main outcome measures: Clinical pregnancy rates. Results: Of a total 265 cycles, 151 cycles were with IUI and 114 others with TIC. No significant difference was found in the overall pregnancy rates between the TIC group (17.5%) and the IUI group (16.6%). Analysis of pregnancy rates according to the type of COH treatments did not demonstrate the advantages of IUI over TIC. Conclusion: Compared to timed intercourse, IUI does not increase the pregnancy rate in couples with PCOS and normal semen analysis treated with COH.
Amir Wiser; Einat Shalom-Paz; Shaune Leigh Reinblatt; Hananel Holzer; Togas Tulandi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-28
Journal Detail:
Title:  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology     Volume:  -     ISSN:  1473-0766     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8807913     Medline TA:  Gynecol Endocrinol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynecology, McGill University , Montreal, Quebec , Canada.
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