| Control of thyrotoxicosis with sotalol. | |
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MedLine Citation:
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PMID: 795363 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sotalol, a beta-adrenergic blocking agent devoid of intrinsic sympathicomimetic activity and local anaesthetic properties, was assessed in a double-blind cross-over study for the symptomatic treatment of 10 patients with thyrotoxicosis. The heart rate and clinical thyrotoxicosis index were significantly lower than with the placebo or with no treatment. The values of free thyroxine and triiodothyronine in the serum did not change. Because of its pure beta-adrenergic blocking effect, sotalol is suitable for the symptomatic treatment of thyrotoxicosis. |
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Authors:
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P Wahlberg; J Wennström; P Ekelund |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Annals of clinical research Volume: 8 ISSN: 0003-4762 ISO Abbreviation: Ann. Clin. Res. Publication Date: 1976 Dec |
Date Detail:
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Created Date: 1977-02-26 Completed Date: 1977-02-26 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0220042 Medline TA: Ann Clin Res Country: FINLAND |
Other Details:
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Languages: eng Pagination: 415-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic Drug Evaluation Heart Rate / drug effects Humans Hyperthyroidism / drug therapy* Sotalol / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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3930-20-9/Sotalol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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