Document Detail


Control of thyrotoxicosis with sotalol.
MedLine Citation:
PMID:  795363     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sotalol, a beta-adrenergic blocking agent devoid of intrinsic sympathicomimetic activity and local anaesthetic properties, was assessed in a double-blind cross-over study for the symptomatic treatment of 10 patients with thyrotoxicosis. The heart rate and clinical thyrotoxicosis index were significantly lower than with the placebo or with no treatment. The values of free thyroxine and triiodothyronine in the serum did not change. Because of its pure beta-adrenergic blocking effect, sotalol is suitable for the symptomatic treatment of thyrotoxicosis.
Authors:
P Wahlberg; J Wennström; P Ekelund
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Annals of clinical research     Volume:  8     ISSN:  0003-4762     ISO Abbreviation:  Ann. Clin. Res.     Publication Date:  1976 Dec 
Date Detail:
Created Date:  1977-02-26     Completed Date:  1977-02-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0220042     Medline TA:  Ann Clin Res     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  415-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Clinical Trials as Topic
Drug Evaluation
Heart Rate / drug effects
Humans
Hyperthyroidism / drug therapy*
Sotalol / therapeutic use*
Chemical
Reg. No./Substance:
3930-20-9/Sotalol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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