Document Detail


Control and quantitation of voluntary weight-lifting performance of rats.
MedLine Citation:
PMID:  12665538     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The present paper describes an exercise model that produces a voluntary hindlimb weight-lifting response. Each rat was operantly conditioned to enter a vertical tube, insert its head into a weighted ring (either 70 g or 700 g), lift the ring until its nose interrupted an infrared detector, and then lower the ring. Load cells measured the external force generated, and displacement transducers measured the vertical displacement of the ring during each lifting and lowering movement. The apparatus and training procedures were computer automated. Peak force, velocity, work, and power were calculated for each movement. Rats in both groups easily acquired the task after 12-15 training sessions, on average, conducted 5 days/wk. Once rats were trained, the lifting patterns were quite stable during several more weeks of posttraining exercise; however, the lighter 70-g load gave rise to more variable performances across rats. Results demonstrate the utility of quantitating the biomechanics of volitional movements and suggest that the present model can establish and maintain controlled repetitive movements necessary for studies of adaptation and/or injury in muscles, tendon, and bone.
Authors:
Oliver Wirth; Erik W Gregory; Robert G Cutlip; G Roger Miller
Related Documents :
19900418 - Exercise exerts neuroprotective effects on parkinson's disease model of rats.
19821018 - Effect of exercise on learning and memory in a rat model of developmental stress.
5328328 - A comparison of the effects of chlorothiazide, quinethazone and placebo on student volu...
20139168 - Aerobic exercise acutely improves insulin- and insulin-like growth factor-1-mediated va...
18787328 - Developing a qigong intervention and an exercise therapy for elderly patients with chro...
3934088 - Comparison of paradoxical salivatory responses to chlorosyle and atropine in a denervat...
Publication Detail:
Type:  Journal Article     Date:  2003-03-28
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  95     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-06-09     Completed Date:  2004-02-02     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  402-12     Citation Subset:  IM    
Affiliation:
Centers for Diseases Control Prevention and National Institute for Occupancy Safety and Health, Morgantown, WV 26505, USA. owirth@cdc.gov
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Biomechanics
Conditioning, Operant / physiology
Hindlimb / physiology*
Joints / physiology
Male
Movement / physiology
Muscle, Skeletal / physiology*
Physical Exertion / physiology*
Rats
Rats, Sprague-Dawley
Reinforcement (Psychology)
Transducers, Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of creatine supplementation and exercise training on fitness in men 55-75 yr old.
Next Document:  Chronic intermittent hypoxia decreases the expression of Na/H exchangers and HCO3-dependent transpor...