| Control of lipids at baseline in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. | |
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MedLine Citation:
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PMID: 19301686 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In order to examine lipids, a major treatment parameter in those with diabetes and heart disease, the authors analyzed baseline data from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. The study consisted of 2368 participants with type 2 diabetes and coronary artery disease from 49 sites in 6 countries (2295 provided lipid measurements). Fifty-nine percent of participants had a low-density lipoprotein (LDL) cholesterol level < 100 mg/dL. Levels of total, LDL, and non-high-density lipoprotein (HDL) cholesterol and triglycerides differed by age group (younger than 55, 55-64, and 65 years and older); they were lowest in those aged 65 years. Women had higher total, LDL, and non-HDL cholesterol values. Education was associated with lower total, LDL, and non-HDL cholesterol levels. LDL cholesterol and triglyceride values were lower in the United States and Canada. Adjustment for age, sex, education level, randomization year, and medication did not eliminate these differences. Geographic variation was seen and was not fully accounted for by demographic or treatment characteristics (all P values < .05). |
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Authors:
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Georgia Pambianco; Manuel Lombardero; Vera Bittner; Alan Forker; Frank Kennedy; Ashok Krishnaswami; Arshag D Mooradian; Rodica Pop-Busui; Jamal S Rana; Annabelle Rodriguez; Michael Steffes; Trevor J Orchard |
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Publication Detail:
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Type: Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Preventive cardiology Volume: 12 ISSN: 1520-037X ISO Abbreviation: Prev Cardiol Publication Date: 2009 |
Date Detail:
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Created Date: 2009-03-23 Completed Date: 2009-04-08 Revised Date: 2010-09-22 |
Medline Journal Info:
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Nlm Unique ID: 9813731 Medline TA: Prev Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 9-18 Citation Subset: IM |
Affiliation:
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Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cholesterol, HDL / blood Cholesterol, LDL / blood Coronary Artery Bypass / methods* Coronary Artery Disease / blood, complications, surgery* Diabetes Mellitus, Type 2 / blood*, complications Female Follow-Up Studies Humans Lipids / blood* Male Middle Aged Prognosis Retrospective Studies Triglycerides / blood |
| Grant Support | |
ID/Acronym/Agency:
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U01 HL061744/HL/NHLBI NIH HHS; U01 HL061744-01A1/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipids; 0/Triglycerides |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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