Document Detail


Control of confounding in the assessment of medical technology.
MedLine Citation:
PMID:  7203778     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Separation of the effects of extraneous variables from the effects of a factor under study (often termed control of confounding) is one of the key prerequisites for validly estimating the magnitude of the study factor's effects. Because of the phenomenon of confounding by indication, confounding of effects of different factors is a common problem in the assessment of medical technology. We give several examples illustrating that the decision of whether a recorded variable is a confounder in a data-set must be decided on the basis of subject-matter knowledge and clinical judgement. There is no alternative to use of such judgement; statistical selection procedures based on significant tests, such as stepwise regression, can be particularly misleading.
Authors:
S Greenland; R Neutra
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of epidemiology     Volume:  9     ISSN:  0300-5771     ISO Abbreviation:  Int J Epidemiol     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-05-13     Completed Date:  1981-05-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802871     Medline TA:  Int J Epidemiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  361-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cesarean Section
Decision Theory
Female
Fetal Monitoring
Humans
Obstetric Labor Complications / diagnosis
Pregnancy
Research Design*
Risk
Technology Assessment, Biomedical / standards*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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