| Control of cell cycle in response to osmostress: lessons from yeast. | |
| | |
MedLine Citation:
|
PMID: 17875412 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To maximize the probability of survival and proliferation, cells coordinate various intracellular activities in response to changes in the extracellular environment. Eukaryotic cells transduce diverse cellular stimuli by multiple mitogen-activated protein kinase (MAPK) cascades. Exposure of cells to stress results in rapid activation of a highly conserved family of MAPKs, known as stress-activated protein kinases (SAPKs). Activation of SAPKs results in the generation of a set of adaptive responses that leads to the modulation of several aspects of cell physiology essential for cell survival, such as gene expression, translation, and morphogenesis. This chapter proposes that regulation of cell cycle progression is another general stress response critical for cell survival. Studies from yeast, both Schizosaccharomyces pombe and Saccharomyces cerevisiae, have served to start understanding how SAPKs control cell cycle progression in response to stress. |
| | |
Authors:
|
J Clotet; F Posas |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Methods in enzymology Volume: 428 ISSN: 0076-6879 ISO Abbreviation: Meth. Enzymol. Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-09-18 Completed Date: 2007-11-05 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 0212271 Medline TA: Methods Enzymol Country: United States |
Other Details:
|
Languages: eng Pagination: 63-76 Citation Subset: IM |
Affiliation:
|
Department of Molecular and Cellular Biology, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anaphase
/
drug effects Cell Cycle / physiology* Cyclin-Dependent Kinases / physiology G1 Phase / physiology G2 Phase / physiology JNK Mitogen-Activated Protein Kinases / physiology MAP Kinase Kinase Kinases / physiology Mitogen-Activated Protein Kinase Kinases / physiology Mitogen-Activated Protein Kinases / physiology Osmotic Pressure* Saccharomyces cerevisiae / physiology* Saccharomyces cerevisiae Proteins / physiology Schizosaccharomyces / physiology* Telophase / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Saccharomyces cerevisiae Proteins; EC 2.7.10.-/HOG1 protein, S cerevisiae; EC 2.7.11.22/Cyclin-Dependent Kinases; EC 2.7.11.24/JNK Mitogen-Activated Protein Kinases; EC 2.7.11.24/Mitogen-Activated Protein Kinases; EC 2.7.11.25/MAP Kinase Kinase Kinases; EC 2.7.12.2/Mitogen-Activated Protein Kinase Kinases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Physiological analysis of bacterial mechanosensitive channels.
Next Document: Bacterial osmosensing transporters.