Document Detail

Control of breathing during exercise in patients with chronic airflow limitation with or without hypercapnia.
MedLine Citation:
PMID:  6628008     Owner:  NLM     Status:  MEDLINE    
Twenty-four patients suffering from chronic obstructive pulmonary disease (COPD) exercised on a bicycle with a progressive increase in load (30 W/min) until dyspnea or exhaustion occurred. Seven subjects were CO2 retainers: PaCO2 greater than or equal to 45 mm Hg at rest and/or during exercise. Fifteen normal subjects were submitted to the same protocol. To make comparison possible, all the parameters studied were calculated at 60 watts. It was concluded that CO2 retention during exercise is not secondary to a decreased respiratory drive but mainly to a lesser increase in VE and to higher VD/VT ratios.
A Van Meerhaeghe; R Sergysels
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Chest     Volume:  84     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  565-70     Citation Subset:  AIM; IM; S    
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MeSH Terms
Hypercapnia / complications,  physiopathology*
Lung Diseases, Obstructive / complications,  physiopathology*
Middle Aged
Physical Exertion*
Respiratory Center / physiopathology
Respiratory Function Tests

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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