Document Detail


The control of food intake: behavioral versus molecular perspectives.
MedLine Citation:
PMID:  19490904     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To meet the continuous demand for energy, organisms use diverse signals to match food intake with energy needs. This paper reviews the effect of satiation signals and adiposity signals on food intake, including how they interact in the brain and how their influence changes with experience. Whereas meal initiation is influenced by external environmental factors, meal size is influenced by an array of signals that can be partitioned according to their reliability in indicating caloric content of food. It is argued that the malleability of satiation signals renders them poor candidates as pharmacological targets to control body weight.
Authors:
Stephen C Woods
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Cell metabolism     Volume:  9     ISSN:  1932-7420     ISO Abbreviation:  Cell Metab.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-03     Completed Date:  2009-08-20     Revised Date:  2014-09-14    
Medline Journal Info:
Nlm Unique ID:  101233170     Medline TA:  Cell Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  489-98     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adiposity / physiology
Animals
Brain / physiology
Eating*
Energy Metabolism
Models, Biological
Satiation / physiology*
Signal Transduction
Grant Support
ID/Acronym/Agency:
DK 017844/DK/NIDDK NIH HHS; DK 067550/DK/NIDDK NIH HHS; R01 DK017844/DK/NIDDK NIH HHS; R01 DK017844-32/DK/NIDDK NIH HHS; R01 DK067550/DK/NIDDK NIH HHS; R01 DK067550-03/DK/NIDDK NIH HHS
Comments/Corrections

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