Document Detail


Contribution of transvaginal ultrasonography and fetal cerebral MRI in a case of congenital cytomegalovirus infection.
MedLine Citation:
PMID:  10867483     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cytomegalovirus is the most common cause of congenital viral infection. In utero this infection is usually suspected on the basis of ultrasound findings. We present a case in which routine ultrasound examination demonstrated a decrease in fetal cephalic dimensions at 32 weeks' gestation in an asymptomatic patient. Transvaginal ultrasound revealed echogenic vessels in the thalami and lesions in the subependymal region. Suspected diagnosis of fetal cytomegalovirus infection was confirmed by positive titers of anti-cytomegalovirus-IgM antibodies in fetal blood and amniotic-fluid PCR studies. Fetal cerebral MRI demonstrated parenchymal atrophy and polymicrogyria. The parents decided to terminate the pregnancy, and necropsy confirmed the diagnosis. Suspicion of CMV fetal infection should prompt transvaginal ultrasound and fetal brain MRI.
Authors:
C Soussotte; B Maugey-Laulom; D Carles; F Diard
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fetal diagnosis and therapy     Volume:  15     ISSN:  1015-3837     ISO Abbreviation:  Fetal. Diagn. Ther.     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2000-08-23     Completed Date:  2000-08-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9107463     Medline TA:  Fetal Diagn Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  219-23     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel.
Affiliation:
Department of Radiology, Centre Hospitalier Universitaire, Bordeaux, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / embryology*,  pathology
Cytomegalovirus Infections / congenital*,  diagnosis*,  ultrasonography
Female
Fetal Diseases / diagnosis,  virology*
Gestational Age
Humans
Magnetic Resonance Imaging*
Pregnancy
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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