Document Detail

Contribution of stereotactic brain biopsies to the diagnosis of presenile dementia.
MedLine Citation:
PMID:  2080358     Owner:  NLM     Status:  MEDLINE    
Precise diagnosis of presenile dementia is a great challenge. The only valuable classification of dementia is the neuropathological one. We present the first series of stereotactic biopsies in 28 presenile patients (18 males, age 39 less than or equal to 58 less than or equal to 69 years, and 10 females, age 23 less than or equal to 52 less than or equal to 66 years). The results demonstrate that the clinical and paraclinical diagnosis (including positron emission tomography scan, neuropsychological examinations, computed tomography scan, electroencephalogram) in only one third of all cases and only in 50% of the Alzheimer and Creutzfeld-Jakob cases. This is very important to be kept in mind when epidemiology or efficacy of drugs are investigated without any neuropathological confirmation.
A Waltregny; A A Maula; J M Brucher
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Stereotactic and functional neurosurgery     Volume:  54-55     ISSN:  1011-6125     ISO Abbreviation:  Stereotact Funct Neurosurg     Publication Date:  1990  
Date Detail:
Created Date:  1991-04-26     Completed Date:  1991-04-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8902881     Medline TA:  Stereotact Funct Neurosurg     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  409-12     Citation Subset:  IM    
Neurosurgical Unit, University of Liége, Belgium.
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MeSH Terms
Alzheimer Disease / pathology*
Biopsy / instrumentation*
Brain / pathology*
Dementia / pathology*
Diagnosis, Differential
Frontal Lobe / pathology
Limbic System / pathology
Middle Aged
Stereotaxic Techniques / instrumentation*
Temporal Lobe / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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