| Contribution of post-receporal cells to the cone a-wave of the human electroretinogram in congenital stationary night blindness and autoimmune-like retinopathy. | |
| | |
MedLine Citation:
|
PMID: 20800609 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
In normal subjects the later part of the cone a-wave to a brief flash increases in amplitude after 50-100 ms darkness due to a contribution from secondary hyperpolarising cells. We recorded these responses along with clinical ON and OFF ERGs in patients with inner retinal dysfunction to see if this part of the a-wave is affected. Patients with autoimmune-like retinopathy and CSNB2 had abnormal ON and OFF responses but the a-wave increased in amplitude in the dark as in normals. Conversely, the OFF-response was normal in CSNB1 but the a-wave did not increase in the dark. Contrary to expectation these results show some hyperpolarising cell function in autoimmune-like disease and CSNB2 and some OFF-pathway abnormality in CSNB1. The a- and d-wave are needed to assess OFF-pathway function. |
| | |
Authors:
|
Keith Bradshaw; Renate Hanitzsch |
Related Documents
:
|
17109159 - The influence of luminance on the multifocal erg. 20711429 - Effects of the ampa antagonist zk 200775 on visual function: a randomized controlled tr... 1928919 - Pigment epithelial function in canine retina. 6716089 - Delayed basal hyperpolarization of cat retinal pigment epithelium and its relation to t... 11097119 - Development of receptoral responses in pigmented and albino guinea-pigs (cavia porcellus). 596319 - Procedures for routine clinical electroretinography (erg) in dogs. 12575959 - Neural correlates of visual localization and perisaccadic mislocalization. 10672479 - Intentional on-line adaptation of stride length in human walking. 3677199 - The photoperiodic entrainment and induction of reproductive rhythms in male blackheaded... |
Publication Detail:
|
Type: Journal Article Date: 2010-08-26 |
Journal Detail:
|
Title: Vision research Volume: 50 ISSN: 1878-5646 ISO Abbreviation: Vision Res. Publication Date: 2010 Nov |
Date Detail:
|
Created Date: 2010-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0417402 Medline TA: Vision Res Country: England |
Other Details:
|
Languages: eng Pagination: 2505-14 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
|
Vision Science, Ophthalmology Department, Addenbrooke's Hospital, Cambridge, UK. k.bradshaw4@btinternet.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Young without plastic surgery: perceptual adaptation to the age of female and male faces.
Next Document: Biological motion influences the visuomotor transformation for smooth pursuit eye movements.