Document Detail


Contribution of ethanol and cigarette smoking to pulmonary dysfunction in chronic alcoholics.
MedLine Citation:
PMID:  3715775     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ethanol is claimed to have a specific damaging effect on the lung and to be at least partially responsible for pulmonary dysfunction in alcoholics. Adequate allowance for the damaging effects of cigarette smoking has not, however, been made hitherto. Pulmonary function studies were undertaken in 27 alcoholic subjects. Although there was a high prevalence of symptoms and abnormalities of pulmonary function, these were largely confined to current smokers: most of those who had never smoked and the ex-smokers who were symptom free and had normal pulmonary function. A case controlled study of alcoholics and matched controls showed no significant difference in pulmonary function between the two groups. It is concluded that the high prevalence of respiratory disease in alcoholics is largely attributable to their smoking habits: no evidence of a specific pulmonary toxic effect of ethanol was identified in the study.
Authors:
D J Lyons; S V Howard; J S Milledge; T J Peters
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Thorax     Volume:  41     ISSN:  0040-6376     ISO Abbreviation:  Thorax     Publication Date:  1986 Mar 
Date Detail:
Created Date:  1986-07-24     Completed Date:  1986-07-24     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0417353     Medline TA:  Thorax     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  197-202     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Alcoholism / physiopathology*
Ethanol / adverse effects*
Female
Humans
Lung / physiopathology
Lung Diseases / etiology*,  physiopathology
Male
Middle Aged
Respiratory Function Tests
Smoking*
Chemical
Reg. No./Substance:
64-17-5/Ethanol
Comments/Corrections

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