Document Detail


Contribution of abdomen and legs to central blood volume expansion in humans during immersion.
MedLine Citation:
PMID:  9292451     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The hypothesis was tested that the abdominal area constitutes an important reservoir for central blood volume expansion (CBVE) during water immersion in humans. Six men underwent 1) water immersion for 30 min (WI), 2) water immersion for 30 min with thigh cuff inflation (250 mmHg) during initial 15 min to exclude legs from contributing to CBVE (WI+Occl), and 3) a seated nonimmersed control with 15 min of thigh cuff inflation (Occl). Plasma protein concentration and hematocrit decreased from 68 +/- 1 to 64 +/- 1 g/l and from 46.7 +/- 0.3 to 45.5 +/- 0.4% (P < 0.05), respectively, during WI but were unchanged during WI+Occl. Left atrial diameter increased from 27 +/- 2 to 36 +/- 1 mm (P < 0.05) during WI and increased similarly during WI+Occl from 27 +/- 2 to 35 +/- 1 mm (P < 0.05). Central venous pressure increased from -3.7 +/- 1.0 to 10.4 +/- 0.8 mmHg during WI (P < 0.05) but only increased to 7.0 +/- 0.8 mmHg during WI+Occl (P < 0.05). In conclusion, the dilution of blood induced by WI to the neck is caused by fluid from the legs, whereas the CBVE is caused mainly by blood from the abdomen.
Authors:
L B Johansen; T U Jensen; B Pump; P Norsk
Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  83     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1997 Sep 
Date Detail:
Created Date:  1997-10-14     Completed Date:  1997-10-14     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol (1985)     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  695-9     Citation Subset:  IM; S    
Affiliation:
Danish Aerospace Medical Centre of Research, Rigshospitalet 7805, DK-2200 Copenhagen, Denmark.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abdomen / anatomy & histology,  blood supply,  physiology*
Adult
Blood Proteins / metabolism
Blood Volume / physiology*
Body Fluids / physiology
Echocardiography
Hematocrit
Hemodilution
Hemodynamics / physiology
Hemoglobins / metabolism
Humans
Immersion / physiopathology*
Leg / anatomy & histology,  blood supply,  physiology*
Male
Regional Blood Flow / physiology
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Hemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Lateral pharyngeal fat pad pressure during breathing in anesthetized pigs.
Next Document:  Role of vagal fibers in the hypoxia-induced increases in end-expiratory lung volume and diaphragmati...