Document Detail

Contrast transcranial Doppler compared to transesophageal echocardiography in detection of right-to-left shunt.
MedLine Citation:
PMID:  22266614     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To assess contrast transcranial Doppler (TCD) for detection of right-to-left shunt (RLSh).
METHODS: We studied 30 patients aged between 25-45 years admitted to Al-Zahra Hospital, affiliated to Isfahan University of Medical Sciences, between May 2003 and May 2005. All patients underwent transesophageal echocardiography (TEE) with contrast and contrast TCD.
RESULTS: Eleven (36.6%) patients had RLSh detected by TEE with contrast, and 19 (63.3%) patients had no shunt by TEE. Eighteen patients (60%) patients had no RLSh by contrast TCD, and 12 (40%) patients had RLSh by contrast TCD. Ten (33.3%) patients had RLSh by contrast TCD and TEE with contrast procedures. One patient had RLSh by TEE, and it was negative on TCD test, and 2 patients were positive on TCD test and negative in TEE. With contrast TEE as the gold standard, the sensitivity of contrast TCD was 90.9% and specificity was 89.4%, with an accuracy of 90%. Meanwhile, the positive predictive value of contrast TCD was 83.3% and the negative predictive value was 94.4%.
CONCLUSION: In our study, the negative predictive value of contrast TCD was excellent. Therefore, this examination is able to exclude RLSh with a high level of confidence.
Ali Hamzehloo; Seid A Mousavi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurosciences (Riyadh, Saudi Arabia)     Volume:  11     ISSN:  1319-6138     ISO Abbreviation:  Neurosciences (Riyadh)     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2012-01-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101252453     Medline TA:  Neurosciences (Riyadh)     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  167-70     Citation Subset:  -    
Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran. Tel. +98 (918) 1623022. Fax. +98 (311) 6684510. E-mail:
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