Document Detail


Contrast-induced nephropathy in patients with type 2 diabetes during coronary angiography: risk-factors and prognostic value.
MedLine Citation:
PMID:  20115935     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: To determine risk factors, prognostic, value prevention of development of contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) in patients with type 2 diabetes mellitus (T2DM). MATERIALS AND METHODS: We have retrospectively analyzed the incidence of CIN developed after PCI in 151 patients T2DM and 50 patients without diabetes. All patients were subjected to thorough clinical examination (including serum creatinine level before and 48 hours after intervention). RESULTS: CIN developed more frequently after PCI in patients with T2DM than in patients of the same age without diabetes at the same baseline renal function, volume of contrast media and hydration status. The risk of developing CIN in patients with T2DM is associated with: heart failure, anemia, volume of contrast media, diuretics use in the peri-procedure period, multiple coronary artery disease, need of interventional procedures. TIDM patients with CIN had faster decline of renal function, more often developed cardiovascular diseases and had lower 24 month survival rate. CONCLUSIONS: High risk of CIN development and its prognostic significance in patients with T2DM determine the necessity of individually evaluated risks for preventive measures during contrast media interventions.
Authors:
Natalia V Zaytseva; Minara S Shamkhalova; Marina V Shestakova; Simon T Matskeplishvili; Elvina F Tugeeva; Ury I Buziashvili; Alexandr D Deev; Ivan I Dedov
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  86 Suppl 1     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  S63-9     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
National Endocrinology Research Center, Moscow, Russian Federation.
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MeSH Terms
Descriptor/Qualifier:
Contrast Media / adverse effects*
Coronary Angiography / adverse effects*
Diabetes Mellitus, Type 2 / blood,  complications,  physiopathology,  radiography*
Diabetic Nephropathies / epidemiology*
Female
Humans
Lipids / blood
Male
Middle Aged
Prognosis
Retrospective Studies
Risk Assessment
Risk Factors
Stroke Volume
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Lipids

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