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Contrast induced exacerbation of renal dysfunction in the advanced chronic kidney disease.
MedLine Citation:
PMID:  23136052     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Contrast media affects renal function, especially in the patients with advanced chronic kidney disease (CKD). The aim of this study was to investigate the characteristics of contrast induced exacerbation of renal dysfunction in the patients with advanced CKD (estimated glomerular filtration rate <30 ml/min/1.73 m(2)). We enrolled 102 advanced CKD patients who underwent cardiac catheterization. Delta creatinine (post-catheterization creatinine minus pre-catheterization creatinine) were calculated. The patients were divided into three groups according to delta creatinine. The highest tertile of the delta creatinine was defined as the exacerbation group. Multivariate logistic regression analyses were performed to find the characteristics of the exacerbation group. Anemia (odds ratio (OR): 15.53, 95 % Confidence Interval (95 %CI): 1.81-133.27, p = 0.01) and proteinuria (OR: 5.91, 95 %CI: 1.64-21.28, p < 0.01) were significant characteristics of the exacerbation group after adjusting confounding factors. In conclusion, anemia and proteinuria were associated with contrast induced exacerbation of renal dysfunction in the advanced CKD patients.
Authors:
Yousuke Taniguchi; Kenichi Sakakura; Hiroshi Wada; Yoshitaka Sugawara; Hiroshi Funayama; Norifumi Kubo; Shin-Ichi Momomura; Junya Ako
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-8
Journal Detail:
Title:  Cardiovascular intervention and therapeutics     Volume:  -     ISSN:  1868-4297     ISO Abbreviation:  Cardiovasc Interv Ther     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101522043     Medline TA:  Cardiovasc Interv Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Amanuma 1-847, Omiya-ku, Saitama, 330-8503, Japan, yousuke_taniguchi@yahoo.co.jp.
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