Document Detail


Contrast enhancement of the inner ear in magnetic resonance images taken at 10 minutes or 4 hours after intravenous gadolinium injection.
MedLine Citation:
PMID:  22201230     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Conclusion. Contrast enhancement of the inner ear by three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) taken 4 h after intravenous gadolinium (Gd) injection was better than when taken at 10 min. Using heavily T2-weighted 3D-FLAIR MRI, visualization of endolymphatic hydrops (EH) was possible in the vestibule and the cochlea after a standard intravenous dose of Gd. Objectives. To define a suitable time point for imaging Gd uptake in the inner ear acquired with heavily T2-weighted 3D-FLAIR MRI after standard intravenous Gd administration. Methods: Using a 3 Tesla MRI unit, heavily T2-weighted 3D-FLAIR MRI images were taken twice at approximately 10 min (conventional timing) and 4 h after intravenous gadodiamide (0.1 mmol/kg) injection in 10 patients with inner ear diseases including Ménière's disease. Results: The 4 h delay increased Gd enhancement of the 3D-FLAIR MRI images of the perilymphatic space in both symptomatic and asymptomatic ears. The increase in Gd enhancement was greater in symptomatic than in asymptomatic ears. Using this heavily T2-weighted 3D-FLAIR technique, EH was observed in both the cochlea and vestibule in images taken 4 h after the intravenous Gd injection.
Authors:
Rui Sano; Masaaki Teranishi; Masahiro Yamazaki; Haruo Isoda; Shinji Naganawa; Michihiko Sone; Mariko Hiramatsu; Tadao Yoshida; Hirokazu Suzuki; Tsutomu Nakashima
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-27
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  -     ISSN:  1651-2251     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Otorhinolaryngology.
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