Document Detail


Contrast-enhanced timing robust acquisition order with a preparation of the longitudinal signal component (CENTRA plus) for 3D contrast-enhanced abdominal imaging.
MedLine Citation:
PMID:  18504734     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To investigate a new image acquisition method that enables an accurate hepatic arterial phase definition and the visualization of contrast agent uptake processes in abdominal organs like liver, spleen, and pancreas. MATERIALS AND METHODS: A 3D turbo gradient echo method where a fat suppression prepulse is followed by the acquisition of several profiles was combined with an elliptical centric k-space ordering technique and 3D dynamic elliptical centric keyhole. The new k-space ordering method (CENTRA+) was validated experimentally. In an initial clinical evaluation phase the method was employed in five patients to assess the accuracy of the hepatic arterial phase definition and the visualization of the contrast uptake processes in dynamic scanning in abdominal organs like liver, spleen, and pancreas. RESULTS: In total, five patients were evaluated using the new k-space order. Our initial results indicate that the new k-space order allows consistent capture of the hepatic arterial phase. In dynamic scanning the extreme short temporal resolution obtained with 3D elliptical centric keyhole enables contrast enhancement to be followed in organs with fast contrast uptake characteristics. CONCLUSION: The elliptical centric nature of the new image acquisition method effectively allows capture of the contrast enhancement processes with good fat suppression.
Authors:
Gabriele M Beck; Jan De Becker; Alun C Jones; Marcus von Falkenhausen; Winfried A Willinek; Jürgen Gieseke
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  27     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-02     Completed Date:  2008-09-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1461-7     Citation Subset:  IM    
Affiliation:
Philips Medical Systems, Best, Netherlands. gabriele.beck@philips.com
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MeSH Terms
Descriptor/Qualifier:
Abdomen / pathology*
Adult
Aged
Algorithms
Contrast Media / administration & dosage*
Female
Gadolinium DTPA / diagnostic use
Hepatic Artery / pathology
Humans
Image Enhancement / methods*
Imaging, Three-Dimensional / methods*
Liver / pathology
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Observer Variation
Pancreas / pathology
Pancreatic Diseases / diagnosis*
Prospective Studies
Reproducibility of Results
Signal Processing, Computer-Assisted
Spleen / pathology
Chemical
Reg. No./Substance:
0/Contrast Media; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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