| Contrast-enhanced hepatic MRI: comparison of half-dose and standard-dose gadolinium DTPA administration in lesion characterization with T1-weighted gradient echo sequences. | |
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MedLine Citation:
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PMID: 10665348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The objective of this article was to compare half-dose (0.05 mm/kg) gadolinium-enhanced dynamic hepatic MR imaging to standard doses (0.10 mm/kg). Eighteen patients for follow-up hepatic MR received 0.05 mm/kg of gadolinium DTPA dynamically with gradient-echo imaging. Imaging parameters were identical to a 0.10-mm/kg study; patients were imaged during multiple phases of contrast enhancement. Two readers assessed for enhancement patterns and characterization. Quantitative signal-to-noise ratios (S/N) were obtained for abdominal viscera and contrast-to-noise ratios (C/N) were obtained on up to three lesions. No significant difference for the arterial dominant phase (P > 0.05) was found. Significant differences were found in all categories during the portal venous phase (except pancreas) and equilibrium phase (except liver). Lesion C/N ratios were not significant at any point (P > 0.05). Sixty-two out of 64 lesions (97%) were identically characterized. Therefore, half-dose dynamic gadolinium-enhanced MR may have diagnostic value. |
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Authors:
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D R De Corato; G A Krinsky; N M Rofsky; J P Earls; J Lebowitz; J C Weinreb |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical imaging Volume: 23 ISSN: 0899-7071 ISO Abbreviation: Clin Imaging Publication Date: 1999 Sep-Oct |
Date Detail:
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Created Date: 2000-02-28 Completed Date: 2000-02-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8911831 Medline TA: Clin Imaging Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 302-10 Citation Subset: IM |
Affiliation:
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Department of Radiology, New York University Medical Center, NY 10017, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Contrast Media / administration & dosage* Diagnosis, Differential Echo-Planar Imaging* Female Gadolinium DTPA / administration & dosage*, diagnostic use Humans Image Enhancement / methods* Injections, Intravenous Liver Circulation Liver Diseases / diagnosis Liver Neoplasms / blood supply, diagnosis* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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