Document Detail


Contrast-enhanced helical CT of the head and neck: improved conspicuity of squamous cell carcinoma on delayed scans.
MedLine Citation:
PMID:  11373235     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We evaluated the impact of delayed scans on the conspicuity of squamous cell carcinoma in helical CT of the head and neck. SUBJECTS AND METHODS: Twenty-seven patients with biopsy-proven squamous cell carcinoma of the head and neck underwent dual-phase helical CT examinations using 100 mL of nonionic contrast material. In all patients, the early phase started 30 sec after the commencement of injection. The patients were assigned to one of two groups in which the delayed phase started either 180 sec (group A, n = 13) or 300 sec (group B, n = 14) after the start of injection. The overall image quality, including vascular opacification and the quality of lesion conspicuity, was determined according to a three-point scoring system. RESULTS: Overall image quality scored better on the early scans (score, 1.4 +/- 0.5) than on the late scans with a 180-sec (score, 1.6 +/- 0.6; p = 0.03) or a 300-sec delay (score, 2.4 +/- 0.5; p = 0.002). Tumor conspicuity scored better on scans with a 180-sec delay (score, 1.4 +/- 0.5) than on the scans with a 30-sec delay (score, 2.3 +/- 0.7; p = 0.02) or the scans with a 300-sec delay (score, 2.3 +/- 0.7; p = 0.03). In eight (62%) of 13 patients in group A and in six (43%) of 14 patients in group B, the tumor was better delineated on the late scans than on the early scans. CONCLUSION: Although early scans provide optimal vascular enhancement and are therefore necessary for helical CT studies of the head and neck, additional delayed scans may improve lesion detection in patients with squamous cell carcinoma of the head and neck.
Authors:
R Groell; O Doerfler; G J Schaffler; W Habermann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  176     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-05-24     Completed Date:  2001-07-12     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1571-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, University Hospital Graz, Auenbruggerplatz 9, A-8036 Graz, Austria.
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MeSH Terms
Descriptor/Qualifier:
Carcinoma, Squamous Cell / radiography*
Contrast Media
Female
Head and Neck Neoplasms / radiography*
Humans
Image Processing, Computer-Assisted
Iohexol / analogs & derivatives,  diagnostic use
Male
Middle Aged
Time Factors
Tomography, X-Ray Computed / methods*
Chemical
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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