Document Detail


Contrast-enhanced magnetic resonance angiography in stroke diagnostics: additional information compared with time-of-flight magnetic resonance angiography?
MedLine Citation:
PMID:  21109990     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
PURPOSE: The aim of this study was a comparison of the diagnostic value of time-of-flight magnetic resonance angiography (TOF-MRA) and contrast-enhanced (CE) MRA in the setting of acute stroke MRI. The hypothesis was that CE-MRA has at least the same diagnostic value as the commonly used TOF-MRA.
MATERIALS AND METHODS: A total of 66 stroke patients underwent MRI up to 24 h after symptom onset and again after 3–6 days. Primary slices and maximum intensity projections (MIP) of both techniques were evaluated separately and in combination by two readers in consensus. The quality of imaging and degree of vascular pathologies were evaluated.
RESULTS: Out of 109 examinations 105 could be evaluated. There were no significant differences in imaging quality in normal vascular segments. For arterial segments distal to an occlusion CE-MRA allowed better visualization of vessels than TOF-MRA. A combined evaluation of both techniques allowed a significantly better assessment than evaluation of images by one technique alone. In contrast to TOF-MRA, CE-MRA included extracranial segments.
CONCLUSION: CE-MRA and TOF-MRA do not differ regarding the evaluation of normal intracranial vessels. CE-MRA provides the advantage of good visualization of vessels distal to occluded segments. Furthermore CE-MRA allows visualization of extracranial vessels and faster image acquisition. TOF-MRA can be equivalently used if the administration of contrast agents is not possible.
Authors:
K Alfke; U Jensen; C Pool; A Rohr; R Brüning; J Weber; T Bartsch; R Stingele; O Jansen
Publication Detail:
Type:  Journal Article     Date:  2010-11-26
Journal Detail:
Title:  Clinical neuroradiology     Volume:  21     ISSN:  1869-1447     ISO Abbreviation:  Clin Neuroradiol     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-05-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526693     Medline TA:  Clin Neuroradiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  5-10     Citation Subset:  IM    
Affiliation:
Institute of Radiology and Neuroradiology, Helios Kliniken Schwerin, Schwerin, Germany. k.alfke@neurorad.uni-kiel.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Side population in MDA-MB-231 human breast cancer cells exhibits cancer stem cell-like properties wi...
Next Document:  Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require...