| Contrast-enhanced MRI and PET-CT in the evaluation of patients with suspected local recurrence of rectal carcinoma. | |
| | |
MedLine Citation:
|
PMID: 20574705 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: This study aimed to evaluate the role of contrast-enhanced magnetic resonance imaging (MRI) and positron emission tomography-computed tomography (PET-CT) in the assessment of local recurrence of rectal cancer. MATERIALS AND METHODS: Among 200 patients scheduled for CT follow-up, 60 (48 low risk; 12 high risk) were selected due to CT findings suspicious for or suggestive of local recurrence. Patients underwent contrast-enhanced MRI and PET-CT within 2 weeks. Biopsy was considered the gold standard in 39 cases and follow-up at 6 and 12 months in the remaining 21. RESULTS: Local recurrence was confirmed by histology in 15 cases (7 low risk; 8 high risk) and was excluded in 21 cases by long-term follow-up and in 24 by histology. Sensitivity, specificity, positive and negative predictive value and accuracy were 86.7%, 68.9%, 48.1%, 93.9% and 73.3% for contrast-enhanced MRI and 93.3%, 68.9%, 50%, 96.9% and 75% for PET-CT. CONCLUSIONS: Contrast-enhanced MRI and PET-CT can help in the detection of local recurrence of rectal cancer, even though their roles in early detection remains debatable, as the value of these techniques in current surveillance protocols is still to be defined. |
| | |
Authors:
|
F Fiocchi; V Iotti; G Ligabue; A Pecchi; G Luppi; B Bagni; F Rivasi; P Torricelli |
Related Documents
:
|
19739235 - Detection of hematogenous bone metastasis in cervical cancer: 18f-fluorodeoxyglucose-po... 16564155 - An audit of fusion ct-pet in the management of colorectal liver metastases. 18697365 - The role of imaging in the pre-operative staging and post-operative follow-up of rectal... 12097455 - Dual time point 18f-fdg pet for the evaluation of pulmonary nodules. 22134535 - (18)f-fdg pet/ct compared to conventional imaging modalities in pediatric primary bone ... 8229915 - Problems associated with ultrasonography of the canine ovary around the time of ovulation. |
Publication Detail:
|
Type: Journal Article Date: 2010-06-23 |
Journal Detail:
|
Title: La Radiologia medica Volume: 115 ISSN: 1826-6983 ISO Abbreviation: Radiol Med Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-10-08 Completed Date: 2010-11-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0177625 Medline TA: Radiol Med Country: Italy |
Other Details:
|
Languages: eng; ita Pagination: 906-19 Citation Subset: IM |
Affiliation:
|
Department of Radiology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy. federica.fiocchi@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Biopsy Carcinoma / surgery Contrast Media / diagnostic use* Female Humans Magnetic Resonance Imaging* Male Middle Aged Neoplasm Recurrence, Local / diagnosis* Positron-Emission Tomography* Predictive Value of Tests Radiopharmaceuticals / diagnostic use* Rectal Neoplasms / surgery Sensitivity and Specificity Tomography, X-Ray Computed* |
| Chemical | |
Reg. No./Substance:
|
0/Contrast Media; 0/Radiopharmaceuticals |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: CT-guided needle biopsy performed with modified coaxial technique in the diagnosis of malignant lymp...
Next Document: Prevalence of extravascular collateral findings during 64-slice CT angiography of the abdominal aort...