| Contrast-enhanced MR imaging of the pancreas. | |
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MedLine Citation:
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PMID: 8673719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recent MR techniques such as breath-hold imaging, fat suppression, and dynamic imaging after intravenous administration of gadolinium chelates have reduced artifacts in the abdomen, resulting in an increased role of MR imaging in the evaluation of pancreatic disease. The extracellular contrast agent gadolinium chelate has been shown to enhance normal pancreatic tissue in a homogeneous fashion. Contrast between normal pancreatic tissue and tumor tissue on T1-weighted images may be improved after administration of gadolinium. Because of the lesser vascularization of pancreatic ductal cancers as compared to the normal glandular tissue, the differences in signal intensity are often greatest in the capillary phase immediately after contrast administration. In addition, the hypervascular nature of islet cell tumors, results in good definition of primary tumor and liver metastases on immediate post-gadolinium images. |
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Authors:
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U Kettritz; R C Semelka |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Magnetic resonance imaging clinics of North America Volume: 4 ISSN: 1064-9689 ISO Abbreviation: Magn Reson Imaging Clin N Am Publication Date: 1996 Feb |
Date Detail:
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Created Date: 1996-08-14 Completed Date: 1996-08-14 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9422762 Medline TA: Magn Reson Imaging Clin N Am Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 87-100 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of North Carolina at Chapel Hill, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media* Edetic Acid / analogs & derivatives, diagnostic use Gadolinium / diagnostic use Gadolinium DTPA Humans Magnetic Resonance Imaging / methods* Manganese / diagnostic use Organometallic Compounds / diagnostic use Pancreas / pathology* Pancreas Transplantation / pathology Pancreatic Diseases / diagnosis* Pancreatic Neoplasms / diagnosis* Pentetic Acid / analogs & derivatives, diagnostic use Pyridoxal Phosphate / analogs & derivatives, diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 119797-12-5/N,N'-bis(pyridoxal-5-phosphate)ethylenediamine-N,N'-diacetic acid; 54-47-7/Pyridoxal Phosphate; 60-00-4/Edetic Acid; 67-43-6/Pentetic Acid; 7439-96-5/Manganese; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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