| Contrast enhanced sonographic patterns of hepatic candidiasis | |
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MedLine Citation:
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PMID: 20517805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: B-mode ultrasound (US) of hepatic candidiasis (HC) shows an uncharacteristic pattern. The aim of this study is to display the pattern of HC by performing contrast-enhanced ultrasound (CEUS). PATIENTS AND METHODS: Between May 2006 and June 2008 HC was diagnosed in 12 patients (4 female, 8 male) by clinical and sonographic findings. The underlying diseases were acute leukemia (n = 10), aplastic anemia (n = 1), and testicular cancer (n = 1) in either the state of complete remission (n = 10) or relapse (n = 2). Due to neutropenic fever after chemotherapy all of the patients had received antifungal therapy. When HC was diagnosed all patients were afebrile and in a recovered hematological constitution. Additional diagnostic procedures were histological examination (n = 5), computed tomography (n = 8) and sonographic follow-up examinations (n = 12). All patients were examined with B-mode US and CEUS. RESULTS: In B-mode US the lesions were hypoechoic (n = 12), multiple (n = 10) and > 1 cm (n = 8) as well as > 2 cm (n = 4) in diameter. During CEUS no enhancement of contrast media in the centre of the lesions was seen in all cases during both phases. Additionally, in the arterial phase, the lesions showed no rim enhancement (n = 3) (type I), an isoechoic rim enhancement (n = 5) (type II), or a hyperechoic rim enhancement (n = 4) (type III). During sonographic follow-up a complete regression of the lesions (n = 9) or a stable disease (n = 2) was seen. One patient died due to a relapse. CONCLUSION: The CEUS pattern of HC is variable but characteristic. Therefore, CEUS should be performed in all patients with suspected HC. |
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Authors:
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C Görg; T Bert; E Klassen; A Neesse; P Barth; A Neubauer |
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Publication Detail:
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Type: English Abstract; Journal Article Date: 2010-06-01 |
Journal Detail:
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Title: Zeitschrift für Gastroenterologie Volume: 48 ISSN: 1439-7803 ISO Abbreviation: Z Gastroenterol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-02 Completed Date: 2010-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0033370 Medline TA: Z Gastroenterol Country: Germany |
Other Details:
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Languages: ger Pagination: 678-82 Citation Subset: IM |
Copyright Information:
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Georg Thieme Verlag KG Stuttgart. New York. |
Affiliation:
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Klinik für Hämatologie, Onkologie und Immunologie, Philipps-Universität Marburg und Universitätsklinikum Giessen und Marburg GmbH, Standort Marburg. |
Vernacular Title:
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Kontrastunterstützte sonografische Befunde bei hepatischer Candidiasis. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Candidiasis / ultrasonography* Contrast Media Female Humans Image Enhancement / methods* Liver Diseases / ultrasonography* Male Middle Aged Reproducibility of Results Sensitivity and Specificity Ultrasonography / methods* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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