| Contrast-Enhanced Dynamic MR Imaging of Uterine Fibroids as a Potential Predictor of Patient Eligibility for MR Guided Focused Ultrasound (MRgFUS) Treatment for Symptomatic Uterine Fibroids. | |
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MedLine Citation:
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PMID: 20847940 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a non-invasive treatment approach for symptomatic uterine fibroids. One imaging characteristic considered in selecting patients who may benefit from MRgFUS of their uterine fibroids is the signal intensity of the fibroid compared with surrounding myometrium on T2-weighted MR images. Previous reports suggest that hyper-intense fibroids are less amenable to MRgFUS compared with iso- or hypo-intense fibroids. In this case study, we utilized contrast-enhanced dynamic MR imaging to further characterize the vascularity of a hyper-intense fibroid. Based on the results of dynamic T1-weighted contrast-enhanced images, we assumed that the hyper-intense appearance resulted from high fluid content rather than high vascularity and predicted that the fibroid would respond to MRgFUS. The patient underwent the MRgFUS without complication and reported significant decrease in fibroid symptoms at 3 and 12 months post-treatment. This case suggests that pre-treatment dynamic contrast-enhanced imaging used in conjunction with T2-weighted imaging may improve the criteria for selecting uterine fibroids amenable to treatment with MRgFUS, potentially leading to improved patient outcomes. |
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Authors:
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Sang-Wook Yoon; Chan Lee; Kyoung Ah Kim; Sang Heum Kim |
Publication Detail:
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Type: Journal Article Date: 2010-08-16 |
Journal Detail:
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Title: Obstetrics and gynecology international Volume: 2010 ISSN: 1687-9597 ISO Abbreviation: Obstet Gynecol Int Publication Date: 2010 |
Date Detail:
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Created Date: 2010-09-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101517078 Medline TA: Obstet Gynecol Int Country: United States |
Other Details:
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Languages: eng Pagination: - Citation Subset: - |
Affiliation:
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Department of Diagnostic Radiology, CHA Bundang Medical Center, CHA University, 351, Yatap-dong, Bundang-gu, Sungnam-si, Gyunggi-do 463-712, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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