| Contractures secondary to immobility: is the restriction articular or muscular? An experimental longitudinal study in the rat knee. | |
| | |
MedLine Citation:
|
PMID: 10638868 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVES: To measure articular structures' contribution to the limitation of range of motion after joint immobility. STUDY DESIGN: Experimental, controlled study involving 40 adult rats that had one knee joint immobilized in flexion for durations of 2, 4, 8, 16, and 32 weeks; 20 rats underwent a sham procedure. The angular displacement was measured both in flexion and extension at three different torques. Myotomy of transarticular muscles allowed isolation of the arthrogenic component of the contracture. RESULTS: A contracture developed in all immobilized knees. The articular structures were incrementally responsible for the limitation in range of motion (from 12.6 degrees +/-6.7 degrees at 2 weeks to 51.4 degrees +/-5.4 degrees at 32 weeks). The myogenic restriction proportionately decreased over time (from 20.1 degrees +/-8.4 degrees at 2 weeks to only 0.8 degrees +/-7.2 degrees at 32 weeks). The increase in the arthrogenic component of contracture was predominant in extension. CONCLUSION: This study quantified the increasing role of arthrogenic changes in limiting the range of motion of joints after immobility, especially as the period of immobility extended past 2 weeks. These data provide a better understanding of joint contracture development and can be used to guide therapeutic approaches. |
| | |
Authors:
|
G Trudel; H K Uhthoff |
Related Documents
:
|
949348 - Effect of phenobarbitone on the nucleocytoplasmic transport of ribonucleic acid in vitro. 1010638 - Effects of heat-stress in rats, iii. on pregnant rats, maternal organs and foetal tissues. 6733498 - Skin or hypothalamus cooling: a behavioral choice by rats. 11099138 - Ringtail in suckling munich wistar fromter rats: a histopathologic study. 10509798 - Cis desensitizes gh induced stat5 signaling in rat liver cells. 20682698 - Identification of a serum-induced transcriptional signature associated with type 1 diab... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Archives of physical medicine and rehabilitation Volume: 81 ISSN: 0003-9993 ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2000 Jan |
Date Detail:
|
Created Date: 2000-02-01 Completed Date: 2000-02-01 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 6-13 Citation Subset: AIM; IM; S |
Affiliation:
|
Department of Medicine, University of Ottawa, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Contracture / etiology, physiopathology* Immobilization / adverse effects* Knee Joint / physiopathology* Male Range of Motion, Articular* Rats Rats, Sprague-Dawley Torque |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Aerobic capacity in adult dermatomyositis/polymyositis patients and healthy controls.
Next Document: Influencing factors and ambulation outcome in patients with dual disabilities of hemiplegia and ampu...