Document Detail

Contraception, Pregnancy and Rare Respiratory Diseases.
MedLine Citation:
PMID:  22771004     Owner:  NLM     Status:  Publisher    
Three percent of rare diseases are pneumopathies. Improvements in survival and quality of life have led to a new situation where patients with rare respiratory diseases want to plan their reproductive lives. The intention of this review is to present the experience accumulated in the field of the reproductive health of these women. In several rare respiratory diseases, a genetic base has been identified. The combination of preimplantation genetic diagnosis, assisted reproduction and molecular biology techniques enable embryos to be studied genetically before being transplanted into the uterus. Therefore, the risk for transmitting a certain disease or chromosome alteration may be avoided in high-risk couples, and prenatal diagnoses may be done by chorionic villus sampling or amniocentesis. As a general rule, contraceptive methods should be personalized by evaluating the general state of female patients as well as their possibilities for pregnancy, complications and the future possibility of lung transplantation. In lymphangioleiomyomatosis and primary pulmonary hypertension, pregnancy is considered a contraindication. In the former, there is a very high risk for pneumothorax and loss of lung function. In the latter, mortality reaches 33%. In cystic fibrosis, it is estimated that each year 4% of patients become pregnant and there is no observed loss in lung function. There are special circumstances in childbirth that should be considered as well as specific anesthesia risks. The present review suggests that the decision about contraceptive methods, pregnancy as a contraindication or conditions for managing a pregnancy should be both individualized and multidisciplinary.
Beatriz Lara; Inocencia Fornet; María Goya; Francisco López; José Ramón De Miguel; María Molina; Pilar Morales; Esther Quintana; Sabina Salicrú; Elena Suárez; Piedad Usetti; Felipe Zurbano
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-7
Journal Detail:
Title:  Archivos de bronconeumologia     Volume:  -     ISSN:  1579-2129     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0354720     Medline TA:  Arch Bronconeumol     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 SEPAR. Published by Elsevier Espana. All rights reserved.
Servicio de Neumología, Hospital Universitario Arnau de Vilanova, Lleida, España.
Vernacular Title:
Anticoncepción, embarazo y enfermedades respiratorias minoritarias.
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