| Continuous-wave Doppler in children with ventricular septal defect: noninvasive estimation of interventricular pressure gradient. | |
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MedLine Citation:
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PMID: 3946259 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Continuous-wave Doppler was used to estimate the pressure gradient between the right and left ventricles in 28 children with ventricular septal defect (VSD). Doppler measurement of maximal velocity was performed during cardiac catheterization and the Doppler-predicted gradient was compared with the peak-to-peak gradient measured simultaneously by catheter. Doppler gradients ranged from 10 to 71 mm Hg and correlated well with measured gradient (r = 0.97, p greater than or equal to 0.001). Fourteen patients had isolated VSD, and in these patients Doppler measurements of gradient allowed accurate estimation of right ventricular pressure (r = 0.93). There was an inverse correlation between the ratio of pulmonary to systemic resistance and maximal velocity (r = -0.77). Thus, continuous-wave Doppler is an accurate means of measuring instantaneous VSD pressure gradient in children with congenital heart disease and can be used to estimate the right ventricular and pulmonary artery pressure in children with isolated VSD. This noninvasive method can be used to distinguish restrictive from nonrestrictive VSD. |
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Authors:
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D J Murphy; A Ludomirsky; J C Huhta |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The American journal of cardiology Volume: 57 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1986 Feb |
Date Detail:
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Created Date: 1986-03-17 Completed Date: 1986-03-17 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 428-32 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Blood Pressure* Child Child, Preschool Echocardiography* Heart Catheterization Heart Defects, Congenital / complications Heart Septal Defects, Ventricular / complications, physiopathology* Heart Ventricles / physiopathology Humans Infant |
| Grant Support | |
ID/Acronym/Agency:
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HL31153/HL/NHLBI NIH HHS; RR-00188/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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