Document Detail

Continuous venovenous hemofiltration in the management of acute decompensation in inborn errors of metabolism.
MedLine Citation:
PMID:  2040923     Owner:  NLM     Status:  MEDLINE    
Continuous venovenous hemofiltration was used to treat two neonates, one with maple syrup urine disease and the other with an inborn error of long-chain fatty acid oxidation. The latter infant had hypoglycemia, hyperammonemia and lactic acidosis. In both cases, acceptable biochemical control was achieved within 8 hours. This therapy offers the potential to overcome acute crises rapidly in a wide range of inborn errors of intermediary metabolism.
G N Thompson; W W Butt; F A Shann; D M Kirby; R D Henning; D W Howells; A Osborne
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  118     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-07-10     Completed Date:  1991-07-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  879-84     Citation Subset:  AIM; IM    
Department of Paediatrics, University of Melbourne, Murcoch Institute, Australia.
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MeSH Terms
Amino Acids / blood
Amino Acids, Branched-Chain / blood
Fatty Acids / metabolism*
Hemofiltration / methods*
Infant, Newborn
Lipid Metabolism, Inborn Errors / blood,  therapy*
Maple Syrup Urine Disease / blood,  therapy*
Reg. No./Substance:
0/Amino Acids; 0/Amino Acids, Branched-Chain; 0/Fatty Acids

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