Document Detail


Continuous venovenous hemodiafiltration for life-threatening mitochondrial myopathy with lactic acidosis and rhabdomyolysis.
MedLine Citation:
PMID:  17722368     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report here the clinical course of a 31-year-old male who recovered from a fulminant form of mitochondrial myopathy with lactic acidosis. The patient was transferred to our hospital with acute dyspnea and a convulsive seizure. On admission, he was in a state of shock, and presented with severe high-output heart failure, acute renal failure, and rhabdomyolysis. Treatment with continuous venovenous hemodiafiltration (CVVHDF) resulted in an excellent response, with no signs of hemodynamic instability. This case suggests that CVVHDF with serial hemodynamic monitoring may be effective in treating hypotensive patients with a life-threatening mitochondrial disorder.
Authors:
Shigeaki Inoue; Masao Nagayama; Hiromichi Aoki; Kozo Tamura; Yosuke Suzuki; Seiji Morita; Yoshihide Nakagawa; Isotoshi Yamamoto; Sadaki Inokuchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of intensive care medicine     Volume:  22     ISSN:  0885-0666     ISO Abbreviation:  J Intensive Care Med     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-08-27     Completed Date:  2007-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8610344     Medline TA:  J Intensive Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  240-4     Citation Subset:  IM    
Affiliation:
Department of Critical Care and Emergency Medicine, Tokai University School of Medicine, Kanagawa, Japan. caf55000@pop12.odn.ne.jp
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MeSH Terms
Descriptor/Qualifier:
Acidosis, Lactic / complications*,  therapy
Adult
Hemofiltration*
Humans
Kidney Failure, Acute / complications,  therapy
Male
Mitochondrial Myopathies / complications,  therapy*
Rhabdomyolysis / complications*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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