Document Detail


Continuous venovenous haemodiafiltration for metformin-induced lactic acidosis.
MedLine Citation:
PMID:  19775050     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 74-year-old man with cardiac failure and renal impairment was admitted to the cardiothoracic intensive care unit with metformin-induced lactic acidosis and shock. He was successfully treated with high-dose (80 ml/kg/hour) continuous venovenous haemodiafiltration. Lactic acidosis is a known complication of metformin and is associated with a high mortality. The use of high-dose continuous venovenous haemodiafiltration for this condition has not previously been reported.
Authors:
L T T Pan; G MacLaren
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anaesthesia and intensive care     Volume:  37     ISSN:  0310-057X     ISO Abbreviation:  Anaesth Intensive Care     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-09-24     Completed Date:  2010-01-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0342017     Medline TA:  Anaesth Intensive Care     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  830-2     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia, National University Hospital, Singapore.
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MeSH Terms
Descriptor/Qualifier:
Acidosis, Lactic* / chemically induced,  therapy
Aged
Critical Illness / therapy
Hemofiltration / methods*
Humans
Hypoglycemic Agents / adverse effects*
Intensive Care Units
Male
Metformin / adverse effects*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Hypoglycemic Agents; 657-24-9/Metformin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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