| Continuous solid-phase extraction and gas chromatography-mass spectrometry determination of pharmaceuticals and hormones in water samples. | |
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MedLine Citation:
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PMID: 20299021 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A semi-automatic flow-based method for the simultaneous determination of 9 pharmaceuticals and 3 hormones in water samples in a single analytical run is proposed. The analytes were retained on a solid-phase extraction sorbent column and 1 microL of the eluate analysed by gas chromatography in combination with electron impact ionization mass spectrometry in the SIM mode. The sorbent used, Oasis-HLB, provided near-quantitative recovery of all analytes. The proposed method was validated with quite good analytical results including low limits of detection (0.01-0.06 ng L(-1) for 100 mL of water) and good linearity (r2>0.993) throughout the studied concentration ranges. The method provided good accuracy (recoveries of 85-103%) and precision (between- and within-day RSD values less than 7%) in the determination of the pharmaceuticals and hormones in tap, river, pond, well, swimming pool and wastewater. |
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Authors:
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A Azzouz; B Souhail; E Ballesteros |
Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-03-03 |
Journal Detail:
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Title: Journal of chromatography. A Volume: 1217 ISSN: 1873-3778 ISO Abbreviation: J Chromatogr A Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-05 Completed Date: 2010-06-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9318488 Medline TA: J Chromatogr A Country: Netherlands |
Other Details:
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Languages: eng Pagination: 2956-63 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Physical and Analytical Chemistry, E.P.S of Linares, University of Ja?n, Alfonso X, El Sabio 28, 23700 Linares, Ja?n, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Environmental Monitoring
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methods* Gas Chromatography-Mass Spectrometry / methods* Hormones / analysis* Limit of Detection Pharmaceutical Preparations / analysis* Solid Phase Extraction / methods* Water Pollutants, Chemical / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Hormones; 0/Pharmaceutical Preparations; 0/Water Pollutants, Chemical |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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