| Continuous pump-driven hemofiltration associated with a decline in alpha-atrial natriuretic peptide. | |
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MedLine Citation:
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PMID: 2946555 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The levels of alpha-atrial natriuretic peptide (ANP) in the right atrium, pulmonary artery, radial artery, and superior vena cava plasma were measured by radioimmunoassay in eight patients with volume-expansion due to different diseases. The alpha-ANP levels were significantly increased, but became decreased after fluid removal by continuous veno-venous hemofiltration. When all alpha-ANP concentrations of different anatomical locations and hemodynamic variables were grouped, pulmonary capillary wedge pressure correlated significantly with all alpha-ANP groups, whereas right atrial mean pressure correlated with alpha-ANP levels in pulmonary artery plasma only. Alpha-ANP concentrations were distinctly lower in superior vena cava plasma than in plasma from the right atrium, pulmonary artery, and radial artery. Since alpha-ANP plays an important role in the homeostasis of sodium and fluid balance, measurement of alpha-ANP concentrations, particularly in right atrium, pulmonary artery, or radial artery plasma, might provide valuable information on the status of the critically ill. |
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Authors:
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R Pacher; M Frass; E Hartter; W Woloszczuk; C Leithner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Critical care medicine Volume: 14 ISSN: 0090-3493 ISO Abbreviation: Crit. Care Med. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-01-06 Completed Date: 1987-01-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0355501 Medline TA: Crit Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1010-4 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Atrial Natriuretic Factor / blood* Blood* Critical Care* Female Hemodynamics Humans Male Middle Aged Radioimmunoassay Ultrafiltration* |
| Chemical | |
Reg. No./Substance:
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85637-73-6/Atrial Natriuretic Factor |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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