Document Detail


Continuous positive airway pressure versus positive end-expiratory pressure in respiratory distress syndrome.
MedLine Citation:
PMID:  333189     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The hemodynamic and respiratory effects of spontaneous ventilation with continuous positive airway pressure (CPAP) and mechanical ventilation with positive end-expiratory pressure (PEEP) were compared in nine patients who had adult respiratory distress syndrome. These patients were capable of maintaining spontaneous ventilation (tidal volume above 300 ml. and PaCO2 below 45 torr). Arterial and mixed venous blood gases, cardiac output, oxygen delivery and consumption, pulmonary artery pressure, and pulmonary wedge pressure were measured in 11 instances, with each patient on 5 or 10 cm. H2O CPAP or PEEP, and in nine instances, with each patient on the ventilator but without PEEP (O PEEP). During CPAP, when compared to PEEP at the same level of end-expiratory pressure, mean PaO2 increased significantly (p less than 0.05) and mean physiological shunt decreased (p less than 0.05). In nine of 11 instances, cardiac output was higher on CPAP than on a corresponding level of PEEP. Thus CPAP was more effective than the same amount of PEEP in improving arterial oxygenation by the lung without adversely affecting cardiac output.
Authors:
D M Shah; J C Newell; R E Dutton; S R Powers
Related Documents :
2111249 - Peep-masks in patients with severe obstructive pulmonary disease: a negative report.
11939809 - Release and activation of matrix metalloproteinase-9 during in vitro mechanical compres...
2656099 - Mediastinal, left, and right atrial pressure variations with different modes of mechani...
9655729 - The pressure-volume curve is greatly modified by recruitment. a mathematical model of a...
7633699 - Effects of peep on liver arterial and venous blood flows.
11455939 - Static and dynamic pressure-volume curves reflect different aspects of respiratory syst...
8946179 - Plantar foot pressures during treadmill walking with high-heel and low-heel shoes.
23637999 - Evolvability is inevitable: increasing evolvability without the pressure to adapt.
14636029 - Periodic breathing induced by arterial oxygen partial pressure oscillations.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  74     ISSN:  0022-5223     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1977-11-25     Completed Date:  1977-11-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  557-62     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Female
Functional Residual Capacity
Humans
Male
Middle Aged
Oxygen Consumption
Positive-Pressure Respiration*
Respiration, Artificial
Respiratory Distress Syndrome, Adult / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prophylactic antibiotics in the treatment of penetrating chest wounds. A prospective double-blind st...
Next Document:  Preservation of canine hearts after warm ischemia (zero to thirty minutes) and one to two days of hy...