| Continuous positive airway pressure administered via face mask in tranquilized dogs. | |
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MedLine Citation:
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PMID: 20955301 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the tolerance of a continuous positive airway pressure (CPAP) mask in tranquilized dogs and compare PaO₂ in arterial blood in dogs receiving oxygen with a regular face mask or CPAP mask set to maintain a pressure of 2.5 or 5 cm H₂O. DESIGN: Prospective, randomized clinical study. SETTING: University teaching hospital. ANIMALS: Sixteen client-owned dogs without evidence of cardiopulmonary disease were studied. INTERVENTIONS: Eight animals were randomly assigned to each of 2 treatment groups: group A received 2.5 cm H₂O CPAP and group B received 5 cm H₂O CPAP after first receiving oxygen (5 L/min) by a regular face mask. Animals were tranquilized with acepromazine 0.05 mg/kg, i.v. and morphine 0.2 mg/kg, i.m.. An arterial catheter was then placed to facilitate blood sampling for pHa, PaO₂, and PaCO₂ determinations before and after treatments. Direct mean arterial pressure, heart rate, respiratory rate, and temperature were also recorded after each treatment. MEASUREMENTS AND MAIN RESULTS: CPAP administration was well tolerated by all animals. The mean arterial pressure, heart rate, respiratory rate, temperature, PaCO₂, and pHa, did not differ at any time point between groups. Differences were seen in oxygenation; in group A, PaO₂ significantly increased from a mean of 288.3 ± 47.5 mm Hg with a standard mask to a mean of 390.3 ± 65.5 mm Hg with the CPAP mask and in group B, PaO₂ increased similarly from 325.0 ± 70.5 to 425.2 ± 63.4 mm Hg (P<0.05); no differences were detected between the 2 CPAP treatments. CONCLUSIONS: In healthy tranquilized dogs noninvasive CPAP is well tolerated and increases PaO₂ above values obtained when using a regular face mask. |
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Authors:
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Angela Briganti; Pierre Melanie; Diego Portela; Gloria Breghi; Khursheed Mama |
Publication Detail:
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Type: Journal Article Date: 2010-09-29 |
Journal Detail:
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Title: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) Volume: 20 ISSN: 1476-4431 ISO Abbreviation: J Vet Emerg Crit Care (San Antonio) Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101152804 Medline TA: J Vet Emerg Crit Care (San Antonio) Country: United States |
Other Details:
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Languages: eng Pagination: 503-8 Citation Subset: IM |
Copyright Information:
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© Veterinary Emergency and Critical Care Society 2010. |
Affiliation:
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Veterinary Clinical Department, University of Veterinary Medicine, San Piero a Grado, Pisa, Italy. abriganti@vet.unipi.it |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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