Document Detail

Continuous monitoring of oxygen tension with a transcutaneous sensor during hypotensive anesthesia.
MedLine Citation:
PMID:  3103366     Owner:  NLM     Status:  MEDLINE    
Transcutaneous oxygen tension (TCPO2) is a useful noninvasive technique for monitoring arterial oxygen tension under stable circulatory conditions. This study was undertaken to determine if TCPO2 is also reliable during sodium nitroprusside-induced hypotension under general anesthesia. Arterial blood gases and TCPO2 were measured prior to inducing hypotension (baseline), at 20-min intervals during hypotension, and when systemic arterial pressure had returned to within 10% of the control (pre-hypotension) value. With induced hypotension, PaO2 and TCPO2 decreased significantly (P less than 0.05), and were well correlated by linear regression (r greater than 0.85); however, regressions were strongly dependent on the individual patient. The mean regression line for all patients as a group was given by TCPO2 = 0.69 PaO2 + 20.7 mmHg (r = 0.93, P less than 0.01); significantly different regressions were obtained for each patient (P less than 0.0001). Comparing changes in TCPO2 versus those in PaO2 (relative change from baseline values) did not substantially reduce the variability among patients. It is concluded that TCPO2 reliably reflects changes in arterial oxygen tension during controlled hypotension under general anesthesia, but that a separate calibration of TCPO2 vs. PaO2, obtained prior to inducing hypotension, may be required for each individual patient.
J Megerman; P T Mihelakos; A N Katsamouris; N R Fahmy; D G Lappas; W M Abbott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  31     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1987 Jan 
Date Detail:
Created Date:  1987-04-15     Completed Date:  1987-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  25-9     Citation Subset:  IM    
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MeSH Terms
Anesthesia, General*
Blood Gas Monitoring, Transcutaneous*
Carbon Dioxide / blood
Hip Prosthesis*
Hypotension, Controlled*
Intraoperative Period
Middle Aged
Nitrous Oxide
Oxygen / blood
Reg. No./Substance:
10024-97-2/Nitrous Oxide; 124-38-9/Carbon Dioxide; 15078-28-1/Nitroprusside; 151-67-7/Halothane; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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