Document Detail

Continuous monitoring of mixed venous oxygen saturation in cardiac surgery.
MedLine Citation:
PMID:  6981449     Owner:  NLM     Status:  MEDLINE    
Serial measurement of mixed venous oxygen saturation is useful in the care of critically ill patients. It is an index of cardiac output and overall tissue perfusion. Previously, lack of refinement of the technology for continuous monitoring of mixed venous oxygen saturation deterred its clinical application. The authors evaluated the Oximetrix ShawTM catheter oximeter system between May 1980 and April 1981 in 84 high-risk and moderately high-risk patients. Fifty-four had undergone only myocardial revascularization while 30 had undergone valvular or combined procedures. In 20 patients with compromised left ventricular function (mean ejection fraction of less than 40%) continuous mixed venous oxygen saturation was compared to hemodynamic parameters in an intraoperative and early postoperative study. The results indicated that satisfactory mixed venous oxygen saturation (more than 65%) correlated with normal hemodynamic measurements including cardiac output and cardiac index. In general, a fall in mixed venous oxygen saturation of more than 10% was noted before the mean blood pressure, heart rate or pulmonary capillary wedge pressure changed. Cardiac output, cardiac index, systemic vascular resistance and left ventricular stroke work index were found to change in association with a change in mixed venous oxygen saturation. A fall (mixed venous oxygen saturation less than 65%) can be related to: (a) abnormal hemodynamic status--reduced cardiac output, hypotension, elevated systemic vascular resistance and arrhythmias, (b) abnormal oxygen demand--shivering, suctioning, positioning and pyrexia and (c) abnormal oxygen supply--anemia, airway obstruction and altered diffusion of oxygen at the alveolar capillary membrane. The Oximetrix system proved reliable. Mixed venous oxygen saturation is a nonspecific indicator of hemodynamic status. Continuous monitoring of the mixed venous oxygen saturation facilitates optimal patient management by immediately alerting intensive care personnel to the development of inadequate tissue perfusion.
W R Jamieson; K W Turnbull; A J Larrieu; W A Dodds; J C Allison; G F Tyers
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  25     ISSN:  0008-428X     ISO Abbreviation:  Can J Surg     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-12-03     Completed Date:  1982-12-03     Revised Date:  2007-08-16    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  538-43     Citation Subset:  IM    
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MeSH Terms
Aortic Aneurysm / surgery
Cardiac Output
Cardiac Surgical Procedures / adverse effects*
Coronary Artery Bypass
Heart Aneurysm / surgery
Heart Valve Prosthesis
Hypothermia, Induced
Middle Aged
Monitoring, Physiologic*
Oxygen / blood
Oxygen Consumption*
Partial Pressure*
Postoperative Complications / diagnosis
Reg. No./Substance:

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