| Continuous monitoring of global left ventricular ejection fraction during percutaneous transluminal coronary angioplasty. | |
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MedLine Citation:
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PMID: 9555774 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Continuous monitoring of left ventricular (LV) function during percutaneous transluminal coronary angioplasty (PTCA) was performed in 40 patients (53 +/- 2 years) with a miniature, nuclear detector system after labeling the patients' red blood cells with technetium-99m. Balloon dilation (113 seconds, range 60 to 240) induced on average a 0.12 ejection fraction (EF) unit (19%) decrease in the LVEF, which was explained by a 34% increase in end-systolic counts. Balloon dilation of the left anterior descending artery (n = 23) produced a decrease in the LVEF of 0.17 +/- 0.13 EF units compared with the decrease of 0.06 +/- 0.07 EF units in patients undergoing dilation of the left circumflex artery (n = 9) and 0.05 +/- 0.04 EF units in patients treated for a stenosis of the right coronary artery (n = 8), (p = 0.02). Balloon deflation was associated with an immediate return to pre-PTCA levels. In 10 patients with 2 identical balloon occlusions, the second occlusion led to a significantly less decrease in the LVEF (0.41 +/- 0.14 vs 0.44 +/- 0.15) and electrocardiographic ST-segment deviation (88 +/- 54 microV vs 65 +/- 42 microV) than the first. We conclude that PTCA is associated with an abrupt transient decrease in the LVEF. The effect of balloon occlusion of the left anterior descending artery is more pronounced than balloon occlusion of the left circumflex and the right coronary arteries. Neither single nor multiple balloon occlusions were associated with post-PTCA global LV dysfunction, whereas the lesser degree of LV dysfunction and electrocardiographic signs of myocardial ischemia during the second of 2 identical balloon occlusions suggests that preconditioning can be induced during PTCA. |
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Authors:
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T B Lindhardt; H Kelbaek; J K Madsen; K Saunamäki; P Clemmensen; B Hesse; N Gadsbøll |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of cardiology Volume: 81 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-05-05 Completed Date: 1998-05-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 853-9 Citation Subset: AIM; IM |
Affiliation:
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Heart Center, Medical Department B, Rigshospitalet, Copenhagen University Hospital, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary* Coronary Disease / physiopathology, radionuclide imaging, therapy* Electrocardiography Erythrocytes Female Heart / radionuclide imaging* Humans Male Middle Aged Monitoring, Physiologic / methods Myocardial Ischemia / physiopathology Stroke Volume / physiology* Technetium / diagnostic use Time Factors Ventricular Dysfunction, Left / physiopathology Ventricular Function, Left / physiology* |
| Chemical | |
Reg. No./Substance:
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7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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