Document Detail


Continuous monitoring of depth of sedation by EEG spectral analysis in patients requiring mechanical ventilation.
MedLine Citation:
PMID:  7826794     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-three patients undergoing intensive therapy had continuous EEG recording in an attempt to assess depth of sedation using spectral analysis. Median power frequency (MPF) and spectral edge frequency (SEF) were calculated and correlated with the clinical sedation score and blood concentration of sedative drug. Fifteen patients received isoflurane and eight midazolam. There was no correlation between MPF or SEF and sedation score or blood concentration of drug. These results suggest that no simple measure of the EEG is likely to correlate with depth of sedation in critically ill patients.
Authors:
E M Spencer; J L Green; S M Willatts
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  73     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-02-21     Completed Date:  1995-02-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  649-54     Citation Subset:  IM    
Affiliation:
Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Consciousness / drug effects
Electroencephalography*
Female
Humans
Intensive Care
Isoflurane / administration & dosage,  blood*
Male
Midazolam / administration & dosage,  blood*
Middle Aged
Monitoring, Physiologic
Respiration, Artificial*
Time Factors
Chemical
Reg. No./Substance:
26675-46-7/Isoflurane; 59467-70-8/Midazolam

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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