| Continuous monitoring of depth of sedation by EEG spectral analysis in patients requiring mechanical ventilation. | |
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MedLine Citation:
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PMID: 7826794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Twenty-three patients undergoing intensive therapy had continuous EEG recording in an attempt to assess depth of sedation using spectral analysis. Median power frequency (MPF) and spectral edge frequency (SEF) were calculated and correlated with the clinical sedation score and blood concentration of sedative drug. Fifteen patients received isoflurane and eight midazolam. There was no correlation between MPF or SEF and sedation score or blood concentration of drug. These results suggest that no simple measure of the EEG is likely to correlate with depth of sedation in critically ill patients. |
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Authors:
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E M Spencer; J L Green; S M Willatts |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: British journal of anaesthesia Volume: 73 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1994 Nov |
Date Detail:
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Created Date: 1995-02-21 Completed Date: 1995-02-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 649-54 Citation Subset: IM |
Affiliation:
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Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Consciousness / drug effects Electroencephalography* Female Humans Intensive Care Isoflurane / administration & dosage, blood* Male Midazolam / administration & dosage, blood* Middle Aged Monitoring, Physiologic Respiration, Artificial* Time Factors |
| Chemical | |
Reg. No./Substance:
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26675-46-7/Isoflurane; 59467-70-8/Midazolam |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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