Document Detail

Continuous, on-line, real-time spectral analysis of SAP signals during cardiopulmonary bypass.
MedLine Citation:
PMID:  7611484     Owner:  NLM     Status:  MEDLINE    
We communicated the application of continuous, on-line, real-time power spectral analysis of systemic arterial pressure (SAP) signals during cardiopulmonary bypass when the heart was functionally but reversibly disconnected from the blood vessels. Based on observations from 15 cases of successfully completed coronary artery bypass grafting procedures, we found that the very low (0.00-0.08 Hz), low (0.08-0.15 Hz)-, high (0.15-0.25 Hz)-, and very high (0.80-1.60 Hz) frequency components of SAP signals exhibited differential changes before, during, and after cardiopulmonary bypass. In particular, the very low-frequency component, which purportedly represents the contribution of vasomotor activity to SAP, presented only a mild decrease in power during hypothermic cardioplegia. Interestingly, the total peripheral resistance also manifested only a slight reduction during the same period. On the other hand, the low-, high-, and very high frequency components were essentially eliminated. These results unveiled an active role for the blood vessels in the maintenance of SAP during cardiopulmonary bypass, possibly as a result of a maintained vasomotor tone as reflected by the sustained very low frequency component of the SAP signals.
M W Yang; T B Kuo; S M Lin; K H Chan; S H Chan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of physiology     Volume:  268     ISSN:  0002-9513     ISO Abbreviation:  Am. J. Physiol.     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-08-14     Completed Date:  1995-08-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370511     Medline TA:  Am J Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  H2329-35     Citation Subset:  IM    
Department of Anesthesiology, National Yang-Ming University, Taipei, Taiwan, Republic of China.
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MeSH Terms
Blood Pressure*
Cardiopulmonary Bypass*
Coronary Artery Bypass*
Heart Arrest, Induced
Heart Rate
Hypothermia, Induced
Intubation, Intratracheal
Models, Cardiovascular*
Muscle Tonus
Muscle, Smooth, Vascular / physiopathology
Myocardial Contraction
Time Factors
Ventricular Function, Left
Ventricular Function, Right

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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