Document Detail

Continuous intrathecal baclofen therapy in children with cerebral palsy - when does improvement emerge?
MedLine Citation:
PMID:  19912148     Owner:  NLM     Status:  In-Process    
AIM: The aim of the study was to explore the timing of effects of intrathecal baclofen therapy in children with cerebral palsy.
METHODS: Thirty five children with severe disabilities with cerebral palsy who started continuous intrathecal baclofen therapy (CITB) were followed for 18 months. Pain, number of awakenings during night, spasticity, GMFM-66 scores and PEDI scores were recorded the day before pump implantation and after 6 and 18 months of treatment respectively.
RESULTS: Introduction of CITB was associated with changes across all ICF dimensions. Reduced pain and improved sleep occurred within 6 months of treatment. Social function improved within 6 months and continued to improve until 18 months of CITB. Mobility also improved, but with a latency.
CONCLUSION: There seems to be a sequence of changes after introduction of continuous intrathecal baclofen in a child with cerebral palsy that may guide the multidisciplinary team in their timing of therapy during post-surgical follow-up.
K Ramstad; R Jahnsen; B Lofterod; O H Skjeldal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1661-5     Citation Subset:  IM    
Copyright Information:
© 2009 The Author(s)/Journal Compilation © 2009 Foundation Acta Paediatrica.
Department of Paediatrics, Oslo University Hospital, Oslo, Norway.
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