| Continuous glucose monitoring in infants of very low birth weight. | |
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MedLine Citation:
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PMID: 18971588 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To evaluate the feasibility and efficacy of a continuous glucose monitoring system (CGMS) in a population of infants of very low birth weight (VLBW). STUDY DESIGN: Infants weighing <or=1,500 g and of <or=32 weeks of gestation were recruited within 24 h of delivery. A subcutaneous sensor connected to a CGMS was inserted and maintained for 7 days or until dysfunction. Therapeutic management followed the usual standard protocols. RESULTS: 38 patients (21 male) were included over 17 months. Their mean gestational age was 27.5 +/- 2.0 weeks and their mean birth weight was 958.3 +/- 205.5 g. Their perinatal histories and complications during admission were unremarkable for extremely premature babies. Continuous monitoring lasted an average of 7.84 +/- 1.99 days per patient. Hyperglycaemia was detected in 22 (57.90%) patients and it lasted a mean of 20.33 +/- 30.13 h, while 14 (36.8%) presented with hypoglycaemia for a mean of 2.45 +/- 2.3 h. CONCLUSIONS: The CGMS gave a safe and useful estimate of glucose levels in VLBW infants, revealing abnormal glucose levels at a much higher rate than expected by usual sampling. However, it was not able to provide real-time glucose concentration data. CGMS may be very useful in providing information on the role of hyper- and hypoglycaemia on short- and long-term outcomes in VLBW infants. |
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Authors:
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Isabel Iglesias Platas; Marta Thió Lluch; Neus Pociello Almiñana; Ana Morillo Palomo; Martí Iriondo Sanz; Xavier Krauel Vidal |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-10-30 |
Journal Detail:
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Title: Neonatology Volume: 95 ISSN: 1661-7819 ISO Abbreviation: - Publication Date: 2009 |
Date Detail:
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Created Date: 2009-03-26 Completed Date: 2009-05-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101286577 Medline TA: Neonatology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 217-23 Citation Subset: IM |
Affiliation:
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Neonatal Unit, Hospital Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona University, Barcelona, Spain. iiglesias@hsjdbcn.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Glucose
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metabolism* Female Gestational Age Humans Hyperglycemia / blood, diagnosis* Hypoglycemia / blood, diagnosis* Infant, Newborn Infant, Very Low Birth Weight / blood* Male Monitoring, Ambulatory / instrumentation, methods* |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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