Document Detail


Continuous glucose monitoring in infants of very low birth weight.
MedLine Citation:
PMID:  18971588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To evaluate the feasibility and efficacy of a continuous glucose monitoring system (CGMS) in a population of infants of very low birth weight (VLBW). STUDY DESIGN: Infants weighing <or=1,500 g and of <or=32 weeks of gestation were recruited within 24 h of delivery. A subcutaneous sensor connected to a CGMS was inserted and maintained for 7 days or until dysfunction. Therapeutic management followed the usual standard protocols. RESULTS: 38 patients (21 male) were included over 17 months. Their mean gestational age was 27.5 +/- 2.0 weeks and their mean birth weight was 958.3 +/- 205.5 g. Their perinatal histories and complications during admission were unremarkable for extremely premature babies. Continuous monitoring lasted an average of 7.84 +/- 1.99 days per patient. Hyperglycaemia was detected in 22 (57.90%) patients and it lasted a mean of 20.33 +/- 30.13 h, while 14 (36.8%) presented with hypoglycaemia for a mean of 2.45 +/- 2.3 h. CONCLUSIONS: The CGMS gave a safe and useful estimate of glucose levels in VLBW infants, revealing abnormal glucose levels at a much higher rate than expected by usual sampling. However, it was not able to provide real-time glucose concentration data. CGMS may be very useful in providing information on the role of hyper- and hypoglycaemia on short- and long-term outcomes in VLBW infants.
Authors:
Isabel Iglesias Platas; Marta Thió Lluch; Neus Pociello Almiñana; Ana Morillo Palomo; Martí Iriondo Sanz; Xavier Krauel Vidal
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-10-30
Journal Detail:
Title:  Neonatology     Volume:  95     ISSN:  1661-7819     ISO Abbreviation:  -     Publication Date:  2009  
Date Detail:
Created Date:  2009-03-26     Completed Date:  2009-05-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101286577     Medline TA:  Neonatology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  217-23     Citation Subset:  IM    
Affiliation:
Neonatal Unit, Hospital Sant Joan de Déu, Fundació Sant Joan de Déu, Barcelona University, Barcelona, Spain. iiglesias@hsjdbcn.org
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MeSH Terms
Descriptor/Qualifier:
Blood Glucose / metabolism*
Female
Gestational Age
Humans
Hyperglycemia / blood,  diagnosis*
Hypoglycemia / blood,  diagnosis*
Infant, Newborn
Infant, Very Low Birth Weight / blood*
Male
Monitoring, Ambulatory / instrumentation,  methods*
Chemical
Reg. No./Substance:
0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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