Document Detail

Continuous cardiac output measurements in the perioperative period.
MedLine Citation:
PMID:  7676783     Owner:  NLM     Status:  MEDLINE    
Management of critically ill patients is based on knowledge of fundamental physiologic variables. Automatized and continuous measurement of these variables is preferable. A new system based upon the thermodilution method has been developed to measure cardiac output automatically and continuously. We evaluated the system in the potentially unstable perioperative period with possible great and rapid changes in cardiac output. Twenty patients, scheduled for open heart or abdominal aortic aneurysm surgery, were included in the study, which was approved by the local ethical committee. The patients were monitored up to 30 hours. At random intervals five, iced, bolus thermodilution cardiac output (BCO) determinations were made and compared to the continuous cardiac output measurements (CCO). Two hundred and thirty-one pairs of data were obtained. The cardiac outputs ranged from 2.5-14.9 l.min-1. The absolute bias was 0.31 l.min-1 (95% limits of agreement -14 l.min-1 to 2.0 l.min-1). The mean relative error was 4.7% with a standard deviation of the relative error of 15.4%. The linear regression was represented by: CCO = 1,1352.BCO-0.36. The correlation coefficient R was 0.90 (P < 0.001). In conclusion, the CCO measurement technique is a promising clinical method. The method is straightforward, requires no calibration, is independent of vascular geometry and measures with its limitations volumetric flow. Finally automatic and continuous patient monitoring provides more information and has potential to reveal previously undetected haemodynamic events.
C J Jakobsen; N C Melsen; E B Andresen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  39     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-10-17     Completed Date:  1995-10-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  485-8     Citation Subset:  IM    
Department of Anaesthesia, Skejby University Hospital, Aarhus, Denmark.
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MeSH Terms
Aortic Aneurysm, Abdominal / surgery
Bias (Epidemiology)
Cardiac Output*
Cardiac Surgical Procedures
Catheterization / instrumentation
Critical Illness
Follow-Up Studies
Linear Models
Middle Aged
Monitoring, Physiologic / instrumentation,  methods*,  statistics & numerical data
Preoperative Care*
Pulmonary Artery
Thermodilution / methods,  statistics & numerical data

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