Document Detail

Continuous ambulatory peritoneal dialysis in familial Mediterranean fever amyloidosis patients with end-stage renal failure: a single-centre experience from Turkey.
MedLine Citation:
PMID:  15627789     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: Familial Mediterranean fever (FMF) is an autosomal recessive disease characterised by recurrent fever attacks and polyserositis which may lead to the development of AA amyloidosis and end-stage renal disease (ESRD). In this study, we aimed to evaluate the efficacy of continuous ambulatory peritoneal dialysis (CAPD) in FMF-amyloidosis patients with ESRD. METHODS: Forty age- and sex-matched patients undergoing CAPD at our centre between 1996 and 2002 were included in the study. Of these, 10 had FMF-amyloidosis, 10 had diabetes mellitus (DM), 10 had chronic glomerulonephritis (CGN) and 10 had chronic interstitial nephritis (CIN). Efficiency of CAPD, development of complications, presence of other diseases and survival were compared. RESULTS: With the onset of ESRD, the frequency of FMF peritonitis attacks decreased, with less attacks occurring during CAPD in FMF-amyloidosis patients (p < 0.05). There was no significant difference between the FMF-amyloidosis group and other groups in terms of efficiency of CAPD, peritoneal function, complications and survival. DM patients had a shorter survival period compared with CGN and CIN patients (p < 0.05), but there was no survival difference between FMF-amyloidosis patients and other groups (p > 0.05). CONCLUSIONS: We conclude that CAPD is an effective and safe renal replacement therapy for FMF-amyloidosis patients with ESRD.
Mehmet Riza Altiparmak; Omer Nuri Pamuk; Rezzan Ataman; Kamil Serdengeçti
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Nephron. Clinical practice     Volume:  98     ISSN:  1660-2110     ISO Abbreviation:  Nephron Clin Pract     Publication Date:  2004  
Date Detail:
Created Date:  2005-01-03     Completed Date:  2005-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101159763     Medline TA:  Nephron Clin Pract     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  c119-23     Citation Subset:  IM    
Copyright Information:
Copyright 2004 S. Karger AG, Basel.
Department of Nephrology, Cerrahpaşa Medical Faculty, University of Istanbul, Istanbul, Turkey.
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MeSH Terms
Amyloidosis, Familial / etiology,  therapy*
Familial Mediterranean Fever / complications,  mortality,  therapy*
Kidney Failure, Chronic / etiology,  therapy*
Peritoneal Dialysis, Continuous Ambulatory*
Peritonitis / etiology,  prevention & control
Survival Rate

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