Document Detail

Continuous Renal Replacement Therapy With Prismaflex HF20 Disposable Set in Children From 4 to 15 kg.
MedLine Citation:
PMID:  21869621     Owner:  NLM     Status:  In-Data-Review    
Continuous venovenous hemodiafiltration (CVVHDF) in infants is challenging due to a lack of specific and widely available technology. There is need for high precision of fluid balance and hemodynamic stability. The aim of this study is to report the first experience with the newly developed Prismaflex HF20 disposable set (HF20 set) in infants with CVVHDF. We provided safe treatment in four infants (4-14 kg) suffering from acute renal failure with the HF20 set. Treatment monitoring included patients' blood pressure, patients' weight change, and fluid balance. The anticoagulation was performed with unfractionated heparin. We used commercially available bicarbonate-buffered solutions as dialysate fluid and substitution fluid. At start and during the treatment, the patients showed hemodynamic stability. Desired fluid balance was achieved in all patients during the treatment periods of 49-102 hours. No complications occurred. This report presents CVVHDF experience on the feasibility and safety of the HF20 set in infants. It can be used in CVVHDF or hemodialysis mode. Treatments were well tolerated in all patients, and flow rate adaptability to infants' needs was very acceptable, and the usage of this device was easy and safe.
Siegfried Rödl; Ingrid Marschitz; Christoph J Mache; Martin Koestenberger; Georg Madler; Gerfried Zobel
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  57     ISSN:  1538-943X     ISO Abbreviation:  ASAIO J.     Publication Date:    2011 Sep-Oct
Date Detail:
Created Date:  2011-08-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  451-5     Citation Subset:  IM    
From the *Department of Paediatrics, Pediatric Intensive Care Unit, Medical University of Graz, Graz; †Department of Paediatrics, Neonatology Unit, Paracelsus Medical University Salzburg, Salzburg; ‡Department of Paediatrics, Nephrology Unit, Medical University of Graz, Graz; and §Department of Paediatric Cardiology, Medical University of Graz, Graz, Austria.
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