Document Detail

Continuous infusion of bupivacaine reduces postoperative morphine use in adolescent idiopathic scoliosis after posterior spine fusion.
MedLine Citation:
PMID:  20881514     Owner:  NLM     Status:  In-Data-Review    
STUDY DESIGN.: Retrospective analysis. OBJECTIVE.: To determine if an infusion of bupivacaine will reduce the need for intravenous opioids following posterior spine fusion. SUMMARY OF BACKGROUND DATA.: Adolescent idiopathic scoliosis is estimated to occur with a frequency of 1% to 3% among the at-risk age group of 10 to 18 years. A small percentage of these patients will require surgical intervention. Data are limited regarding continuous infusion of local anesthetic after posterior spine fusion for pain control. METHODS.: Retrospective review of children 10 to 18 years with idiopathic scoliosis admitted to a tertiary care, 20-bed pediatric intensive care unit (P pediatric intensive care unit), following posterior spine fusion. The primary outcome was postoperative opioid use stratified by the presence of a catheter for continuous bupivacaine. Secondary outcomes included pain scores, side effect management, depth of catheter placement, and fluid resuscitation. RESULTS.: Two hundred and forty-four children were eligible, 129 received a catheter for continuous bupivacaine, 115 did not. There were no differences in demographics. Significantly fewer patients receiving bupivacaine required a continuous basal infusion of morphine (32.6% vs. 85.2%, P < 0.001) resulting in an overall reduction opioid use on postoperative day 1 (18.9 vs. 26.4 mg, P < 0.001). Overall, pain scores were low in both groups. Limiting the analysis to only those with a bupivacaine catheter, the depth of catheter placement did not impact postoperative opioid use (P > 0.15). CONCLUSION.: The use of a continuous infusion of bupivacaine provided good analgesia with low pain scores. The significant reduction in basal morphine use may reflect a replacement by bupivacaine, although this is limited by potential treatment bias. Multivariate analysis was required to control for ongoing changes in anesthesia practice over the many years of the study. The optimal depth of catheter placement is unclear from this analysis and should be studied prospectively.
Patrick A Ross; Brendan M Smith; Vernon T Tolo; Robinder G Khemani
Related Documents :
19546674 - Bilateral extraoral, infraorbital nerve block for postoperative pain relief after cleft...
19542094 - Reward contrast in delay and probability discounting.
11561264 - Analgesic effects of low-dose ropivacaine for interscalene brachial plexus block for ou...
22183994 - Treatment of diffuse diabetic maculopathy with intravitreal triamcinolone and laser pho...
9040474 - Investigations on subjective and objective cyclorotatory changes after inferior oblique...
19952384 - Evaluation of published reports of foam sclerotherapy: what do we know conclusively?
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Spine     Volume:  36     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1478-83     Citation Subset:  IM    
* Divisions of Critical Care Medicine † Orthopedic Surgery, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  CYP1A2 is more variable than previously thought: a genomic biography of the gene behind the human dr...
Next Document:  Scoliosis in adults aged forty years and older: prevalence and relationship to age, race, and gender...