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Continuous flow organic synthesis under high-temperature/pressure conditions.
MedLine Citation:
PMID:  20411525     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Microreactor technology and continuous flow processing in general are key features in making organic synthesis both more economical and environmentally friendly. When preformed under a high-temperature/pressure process intensification regime many transformations originally not considered suitable for flow synthesis owing to long reaction times can be converted into high-speed flow chemistry protocols that can operate at production-scale quantities. This Focus Review summarizes the state of the art in high-temperature/pressure microreactor technology and provides a survey of successful applications of this technique from the recent synthetic organic chemistry literature.
Authors:
Tahseen Razzaq; C Oliver Kappe
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chemistry, an Asian journal     Volume:  5     ISSN:  1861-471X     ISO Abbreviation:  Chem Asian J     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-02     Completed Date:  2010-09-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101294643     Medline TA:  Chem Asian J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1274-89     Citation Subset:  -    
Affiliation:
Christian Doppler Laboratory for Microwave Chemistry (CDLMC) and Institute of Chemistry, Karl-Franzens-University Graz, Heinrichstrasse 28, A-8010 Graz, Austria.
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