| Continuation with cotrimoxazole prophylaxis for the prevention of opportunistic infections in HIV-infected persons in rural Zimbabwe: feasibility, obstacles and opportunities. | |
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MedLine Citation:
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PMID: 17453586 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We examined the outcomes of a World Health Organization (WHO) recommended programme offering cotrimoxazole (CTM) prophylaxis to 908 HIV-positive individuals in rural Zimbabwe, who accepted enrolment in the treatment programme. Outcomes included duration in programme, time between visits, relationship and marital status. Mean duration of participation in the programme was 224 days. The mean time between visits decreased from 11.2 weeks, between visit 1 and 2, to 4.3 weeks between visit 11 and 12. Statistical analysis showed significant positive correlations between duration in programme and participant age, participant relationship status and the partner's state of affairs. Statistical analysis showed no significant correlation between duration in programme and gender. Results indicate that if continuation is demonstrated for the first 4 to 6 months, participants will continue with the CTM programme. Results also reflect the constrained feasibility of CTM prophylaxis in rural Africa as well as the need to target subpopulations, such as young people, patients and their spouses for focused HIV/AIDS education initiatives. |
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Authors:
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I Alkatout; R Vineberg; U Schulz; M Anlauf; P Thistle |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: AIDS care Volume: 19 ISSN: 0954-0121 ISO Abbreviation: AIDS Care Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-04-24 Completed Date: 2007-07-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8915313 Medline TA: AIDS Care Country: England |
Other Details:
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Languages: eng Pagination: 478-81 Citation Subset: IM; X |
Affiliation:
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Department of Pathology, University Hospital of Schleswig-Holstein, Kiel, Germany. ialkatout@path.uni-kiel.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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AIDS-Related Opportunistic Infections
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prevention & control* Adolescent Adult Aged Anti-Infective Agents / therapeutic use Child Child, Preschool Feasibility Studies Female Humans Infant Infant, Newborn Male Middle Aged Rural Health Social Environment Trimethoprim-Sulfamethoxazole Combination / pharmacokinetics, therapeutic use* Zimbabwe |
| Chemical | |
Reg. No./Substance:
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0/Anti-Infective Agents; 8064-90-2/Trimethoprim-Sulfamethoxazole Combination |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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